Investigation of local radiation injuries in DNA by the method of thermal separation of spirals
By the method of thermal separation of strands a study was made of the local injuries in the DNA macromolecule caused by x-ray and ultraviolet irradiation. By analysis of the degradation kinetics and flexibility of the initial and final products it was shown that A-irradiation causes no cross linkin...
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| Veröffentlicht in: | Bulletin of experimental biology and medicine 1963-11, Vol.54 (5), p.1232-1235 |
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| container_end_page | 1235 |
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| container_issue | 5 |
| container_start_page | 1232 |
| container_title | Bulletin of experimental biology and medicine |
| container_volume | 54 |
| creator | Ryabchenko, N. I. Tseitlin, P. I. Yaskevich, A. G. |
| description | By the method of thermal separation of strands a study was made of the local injuries in the DNA macromolecule caused by x-ray and ultraviolet irradiation. By analysis of the degradation kinetics and flexibility of the initial and final products it was shown that A-irradiation causes no cross linking preventing the separation of DNA strands; at the same time irradiation leads to the appearance of solitar breaks in polynucleotide chains. Finally, in ultraviolet irradiation thermostable cross-linking is formed, preventing the separation of the two-stranded structure. |
| doi_str_mv | 10.1007/BF00785594 |
| format | Article |
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Finally, in ultraviolet irradiation thermostable cross-linking is formed, preventing the separation of the two-stranded structure.</description><identifier>ISSN: 0007-4888</identifier><identifier>EISSN: 1573-8221</identifier><identifier>DOI: 10.1007/BF00785594</identifier><language>eng</language><subject>BIOLOGY AND MEDICINE ; CONFIGURATION ; DNA ; MOLECULES ; NUCLEIC ACIDS ; RADIATION EFFECTS ; REACTION KINETICS ; ULTRAVIOLET RADIATION ; X RADIATION</subject><ispartof>Bulletin of experimental biology and medicine, 1963-11, Vol.54 (5), p.1232-1235</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c217t-d234373b54a4290e2141a99f38ad853852d9cca81b7a6b1bff2f813803613dd63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,777,781,882,27905,27906</link.rule.ids><backlink>$$Uhttps://www.osti.gov/biblio/4113585$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Ryabchenko, N. 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Finally, in ultraviolet irradiation thermostable cross-linking is formed, preventing the separation of the two-stranded structure.</description><subject>BIOLOGY AND MEDICINE</subject><subject>CONFIGURATION</subject><subject>DNA</subject><subject>MOLECULES</subject><subject>NUCLEIC ACIDS</subject><subject>RADIATION EFFECTS</subject><subject>REACTION KINETICS</subject><subject>ULTRAVIOLET RADIATION</subject><subject>X RADIATION</subject><issn>0007-4888</issn><issn>1573-8221</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1963</creationdate><recordtype>article</recordtype><recordid>eNpFUE1LAzEUDKJgXb34C4JHYTUvH7vZY61WC0Uveg7ZfNiUdrckUei_N6WilzdvhjcDbxC6BnIHhLT3D_MypRAdP0ETEC2rJaVwiiak6DWXUp6ji5TWB0oamCC1GL5dyuFT5zAOePR4Mxq9wVHbcJTCsP6KwaWy4MfXKe73OK8c3rq8Gu3BUFjcFktyOx3_YtIuRL1Jl-jMF3BXv1ihj_nT--ylXr49L2bTZW0otLm2lHHWsl5wzWlHHAUOuus8k9pKwaSgtjNGS-hb3fTQe0-9BCYJa4BZ27AK3Rxzx_KMSiZkZ1ZmHAZnsuIATJSYCt0ej0wcU4rOq10MWx33Cog69Kf--2M_Yq9h3A</recordid><startdate>196311</startdate><enddate>196311</enddate><creator>Ryabchenko, N. 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Finally, in ultraviolet irradiation thermostable cross-linking is formed, preventing the separation of the two-stranded structure.</abstract><doi>10.1007/BF00785594</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-4888 |
| ispartof | Bulletin of experimental biology and medicine, 1963-11, Vol.54 (5), p.1232-1235 |
| issn | 0007-4888 1573-8221 |
| language | eng |
| recordid | cdi_osti_scitechconnect_4113585 |
| source | Springer Online Journals Complete |
| subjects | BIOLOGY AND MEDICINE CONFIGURATION DNA MOLECULES NUCLEIC ACIDS RADIATION EFFECTS REACTION KINETICS ULTRAVIOLET RADIATION X RADIATION |
| title | Investigation of local radiation injuries in DNA by the method of thermal separation of spirals |
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