Deubiquitinating enzyme USP46 suppresses the progression of hepatocellular carcinoma by stabilizing MST1

The deubiquitinating enzyme USP46 (ubiquitin-specific protease 46) is implicated in various cancers. However, its role and regulatory mechanism in HCC (hepatocellular carcinoma) are still unknown. In this study, we showed that USP46 is downregulated in HCC tissues and that low USP46 levels are assoc...

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Veröffentlicht in:	Experimental cell research 2021-08, Vol.405 (1), p.112646-112646, Article 112646
Hauptverfasser:	Qiu, Yumin, Huang, Dan, Sheng, Yanling, Huang, Jinshi, Li, Nuoya, Zhang, Shouhua, Hong, Zhengdong, Yin, Xiangbao, Yan, Jinlong
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES ANIMAL TISSUES CELL PROLIFERATION Deubiquitinating enzyme Hepatocellular carcinoma HEPATOMAS IN VITRO IN VIVO INHIBITION METASTASES Metastasis MST1 PATIENTS PHOSPHOTRANSFERASES Proliferation USP46
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