Heterogeneous response of cancer-associated fibroblasts to the glucose deprivation through mitochondrial calcium uniporter

Cancer-associated fibroblasts (CAFs) are an abundant component of the tumor microenvironment and have distinct features from normal fibroblasts (NFs). However, the discriminative nature of heterogeneous CAFs under glucose starvation remains unknown. In this study, we investigated the changes in the...

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Veröffentlicht in:	Experimental cell research 2021-09, Vol.406 (2), p.112778-112778, Article 112778
Hauptverfasser:	Hwang, Sung-Hyun, Yang, Yeseul, Jung, Jae-Ha, Kim, Yongbaek
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES ANTINEOPLASTIC DRUGS APOPTOSIS ATP CALCIUM Cancer-associated fibroblasts CELL PROLIFERATION CHELATES CONCENTRATION RATIO FIBROBLASTS GLUCOSE Glucose-deficient condition HOMEOSTASIS LUNGS MITOCHONDRIA Mitochondrial calcium Mitochondrial calcium uniporter NEOPLASMS SKIN TGF-β
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