Galectin-1 secreted by bone marrow-derived mesenchymal stem cells mediates anti-inflammatory responses in acute airway disease

The hallmarks of allergic airway disease (AAD) include infiltration of inflammatory cells into the bronchoalveolar space. Bone marrow derived mesenchymal stem cells (BMSCs) show anti-inflammatory properties in AAD. In addition, galectin-1 (Gal-1) is a lectin significantly upregulated upon inflammati...

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Veröffentlicht in:	Experimental cell research 2021-10, Vol.407 (1), p.112788, Article 112788
Hauptverfasser:	Ge, Xiahui, Shi, Kehua, Hou, Jia, Fu, Youhui, Xiao, Hua, Chi, Feng, Xu, Jing, Cai, Feng, Bai, Chong
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Acute airway disease Acute Disease Animals Anti-Inflammatory BONE MARROW Bone Marrow - metabolism Bone Marrow Cells - cytology Cytokines - metabolism Disease Models, Animal DRUGS ENZYME IMMUNOASSAY FEMUR Galectin 1 - metabolism Galectin-1 IN VITRO IN VIVO INFLAMMATION Inflammation - chemically induced Inflammation - metabolism LIPOPOLYSACCHARIDES Lipopolysaccharides - pharmacology Lung - metabolism Lung - pathology LUNGS LYMPHOKINES Male Mesenchymal Stem Cell Transplantation - methods Mesenchymal stem cells Mesenchymal Stem Cells - cytology MICE Mice, Inbred BALB C OVALBUMIN PATHOGENESIS SECRETION Signal Transduction - physiology STEM CELLS
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