Abnormalities of the serotonergic system in diacylglycerol kinase δ-deficient mouse brain

We previously reported that brain-specific diacylglycerol kinase (DGK) δ-knockout (KO) mice showed obsessive-compulsive disorder (OCD)-like behaviors, which were alleviated by a serotonin (5-HT) transporter (SERT) inhibitor. However, the molecular mechanisms causing the OCD-like abnormal behaviors r...

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Veröffentlicht in:	Biochemical and biophysical research communications 2018-03, Vol.497 (4), p.1031-1037
Hauptverfasser:	Lu, Qiang, Komenoi, Suguru, Usuki, Takako, Takahashi, Daisuke, Sakane, Fumio
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT 60 APPLIED LIFE SCIENCES CEREBRAL CORTEX Diacylglycerol kinase HYDROXYLASES MICE Monoamine oxidase OXIDASES PHOSPHOTRANSFERASES SEROTONIN Serotonin transporter TRYPTOPHAN Tryptophan hydroxylase
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