Autophagy activation facilitates mechanical stimulation-promoted osteoblast differentiation and ameliorates hindlimb unloading-induced bone loss

Autophagy has been indicated to be involved in regulating bone metabolism. However, little is known about the role of autophagy in mechanical stimulation-influenced osteoblast differentiation and bone formation. In the present study, we first demonstrated that autophagy activation was essential for...

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Veröffentlicht in:	Biochemical and biophysical research communications 2018-04, Vol.498 (3), p.667-673
Hauptverfasser:	Zhou, Zezhu, Shi, Guixun, Zheng, Xinfeng, Jiang, Shengdan, Jiang, Leisheng
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Autophagy BONE MARROW CONNECTIVE TISSUE CELLS Mechanical stretching METABOLISM Osteoblastic differentiation OSTEOPOROSIS STEM CELLS
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