FoxG1 facilitates proliferation and inhibits differentiation by downregulating FoxO/Smad signaling in glioblastoma

To investigate the effects and underlying molecular mechanisms of FoxG1 expression on glioblastoma multiforme (GBM) models. Expression levels of FoxG1 and other cancer-related biomarkers were evaluated by qRT-PCR, immunoblotting and immunohistochemistry. Crystal violet staining and MTT assay and wer...

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Veröffentlicht in:	Biochemical and biophysical research communications 2018-09, Vol.504 (1), p.46-53
Hauptverfasser:	Wang, Lei, Wang, Jingchao, Jin, Tong, Zhou, Yi, Chen, Qianxue
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES CELL PROLIFERATION Drug resistance DRUGS FoxO1-/Smad signaling Glioblastoma GLIOMAS Tumor differentiation Tumor proliferation
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