LINC00662 promotes gastric cancer cell growth by modulating the Hippo-YAP1 pathway

Long non-coding RNAs (lncRNAs) function as vital regulators of the progression of various diseases, particularly cancers. In the present study, utilizing the Cancer Genome Atlas (TCGA) data set and a series of cell experiments and clinical tissue samples assays, we found that LINC00662 expression wa...

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Veröffentlicht in:	Biochemical and biophysical research communications 2018-11, Vol.505 (3), p.843-849
Hauptverfasser:	Liu, Zhen, Yao, Yangyang, Huang, Shanshan, Li, Li, Jiang, Bailing, Guo, Hui, Lei, Wan, Xiong, Jianping, Deng, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Adaptor Proteins, Signal Transducing - metabolism Adaptor Proteins, Signal Transducing - physiology Cell Line, Tumor CELL PROLIFERATION Gastric cancer GASTROINTESTINAL TRACT Hippo Humans LINC00662 MicroRNAs - metabolism MicroRNAs - physiology miR-497-5p NEOPLASMS Phosphoproteins - metabolism Phosphoproteins - physiology Prognosis Protein-Serine-Threonine Kinases - metabolism Protein-Serine-Threonine Kinases - physiology RNA RNA, Long Noncoding - analysis RNA, Long Noncoding - pharmacology Stomach Neoplasms - pathology Transcription Factors
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