Human umbilical cord-derived mesenchymal stem cells protect from hyperoxic lung injury by ameliorating aberrant elastin remodeling in the lung of O2-exposed newborn rat

The incidence and mortality rates of bronchopulmonary dysplasia (BPD) remain very high. Therefore, novel therapies are imminently needed to improve the outcome of this disease. Human umbilical cord-derived mesenchymal stem cells (UC-MSCs) show promising therapeutic effects on oxygen-induced model of...

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Veröffentlicht in:	Biochemical and biophysical research communications 2018-01, Vol.495 (2), p.1972-1979
Hauptverfasser:	Hou, Chen, Peng, Danyi, Gao, Li, Tian, Daiyin, Dai, Jihong, Luo, Zhengxiu, Liu, Enmei, Chen, Hong, Zou, Lin, Fu, Zhou
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Bronchopulmonary dysplasia Elastin FIBROBLASTS INJURIES LUNGS NEONATES RATS STEM CELLS TGF-β1 UC-MSCs α-SMA
Online-Zugang:	Volltext
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