Long non-coding RNA RMST silencing protects against middle cerebral artery occlusion (MCAO)-induced ischemic stroke

Long non-coding RNAs (lncRNAs) have emerged as major regulators in neurological diseases, and clarifying their roles in cerebral ischemic injury may provide novel targets for treating ischemic stroke. In this study, we mainly studied the role of lncRNA-RMST in middle cerebral artery occlusion (MCAO)...

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Veröffentlicht in:	Biochemical and biophysical research communications 2018-01, Vol.495 (4), p.2602-2608
Hauptverfasser:	Hou, Xiao-Xia, Cheng, Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Animals BRAIN CEREBRAL ARTERIES Gene Silencing Genetic Therapy - methods GLUCOSE Infarction, Middle Cerebral Artery - physiopathology Infarction, Middle Cerebral Artery - prevention & control ISCHEMIA Ischemic stroke Long non-coding RNA Male MICE Mice, Inbred C57BL Middle cerebral artery occlusion NERVE CELLS Neuroprotection Recovery of Function - physiology RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Treatment Outcome
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