SALL4 suppresses reactive oxygen species in pancreatic ductal adenocarcinoma phenotype via FoxM1/Prx III axis

Pancreatic ductal adenocarcinoma (PDAC) is a major malignant phenotype in pancreatic cancer, which is one of the most death causes by cancer in the world. PDAC developed from pancreatic intra-epithelial neoplasms (PanINs) and poorly diagnosed at early stages. Beside of high drug resistance, metastas...

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Veröffentlicht in:	Biochemical and biophysical research communications 2018-09, Vol.503 (4), p.2248-2254
Hauptverfasser:	Huynh, Do Luong, Zhang, Jiao Jiao, Chandimali, Nisansala, Ghosh, Mrinmoy, Gera, Meeta, Kim, Nameun, Park, Yang Ho, Kwon, Taeho, Jeong, Dong Kee
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Carcinoma, Pancreatic Ductal - metabolism CARCINOMAS Cell Movement Cell Proliferation Cell Transdifferentiation Forkhead Box Protein M1 - metabolism FoxM1 Humans Metastasis MITOCHONDRIA Neoplasm Metastasis PANCREAS Pancreatic ductal adenocarcinoma Peroxiredoxin III Peroxiredoxin III - metabolism Phenotype PROTEINS Reactive Oxygen Species - antagonists & inhibitors SALL4 Transcription Factors - physiology
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