Assessment of the hepatocytic differentiation ability of human skin-derived ABCB5+ stem cells

The continuously decreasing willingness for liver donation aggravates treatment of end-stage liver diseases requiring organ transplantation as the only curative strategy. Cell therapy approaches using human hepatocytes or stem cell-derived hepatocyte-like cells may be a therapeutic option out of thi...

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Veröffentlicht in:	Experimental cell research 2018-08, Vol.369 (2), p.335-347
Hauptverfasser:	Tietze, Lysann, Winkler, Sandra, Hempel, Madlen, Kluth, Mark Andreas, Tappenbeck, Nils, Ganss, Christoph, Dooley, Steven, Christ, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES ABCB5 CELL DIFFERENTIATION Cell therapy Hepatic transplantation LIVER CELLS Liver injury MICE MORPHOGENESIS SKIN Stem cell differentiation STEM CELLS
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