Molecular Architecture and Conformational Flexibility of Human RNA Polymerase II

Transcription by RNA polymerase II (RNAPII) is a central process in eukaryotic gene regulation. While atomic details exist for the yeast RNAPII, characterization of the human complex lags behind, mostly due to the inability to obtain large quantities of purified material. Although the complexes have...

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Veröffentlicht in:	Structure (London) 2006-11, Vol.14 (11), p.1691-1700
Hauptverfasser:	Kostek, Seth A., Grob, Patricia, De Carlo, Sacha, Lipscomb, J. Slaton, Garczarek, Florian, Nogales, Eva
Format:	Artikel
Sprache:	eng
Schlagworte:	Cryoelectron Microscopy DNA Fungal Proteins - chemistry HeLa Cells Humans Image Processing, Computer-Assisted Imaging, Three-Dimensional Microscopy, Electron Models, Molecular Molecular Conformation Polymera Protein Conformation RNA Polymerase II - chemistry Transcription, Genetic
Online-Zugang:	Volltext
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