A Facile Synthesis of Itaconic Acid Based Biodegradable Co-polyesters: An In-Vitro Anticancer Evaluation and Controlled Drug Delivery System

A series of aliphatic co-polyesters were prepared via one-step polycondensation reaction of itaconic acid, 1,4-cyclohexane dimethanol and diols using titanium tetraisopropoxide (TTIP) as a catalyst. The chemical structure of the repeating units present in the polymer chains were confirmed by FTIR, 1...

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Veröffentlicht in:	Journal of polymers and the environment 2019-12, Vol.27 (12), p.2756-2768
Hauptverfasser:	Veerabagu, Udayakumar, Jaikumar, Gowsika, Fushen, Lu
Format:	Artikel
Sprache:	eng
Schlagworte:	Aliphatic compounds Anticancer properties Antitumor activity Biodegradability BIODEGRADATION Breast cancer CALORIMETRY Cancer CARBON 13 CARCINOMAS CATALYSTS Chemistry Chemistry and Materials Science CITRATES Citric acid CYCLOHEXANE Degradation Differential scanning calorimetry Diols Drug carriers DRUG DELIVERY Drug delivery systems Environmental Chemistry Environmental Engineering/Biotechnology FOURIER TRANSFORM SPECTROMETERS Glass transition temperature GLYCOLS HYDROGEN 1 Industrial Chemistry/Chemical Engineering INFRARED SPECTRA ITACONIC ACID MAMMARY GLANDS MATERIALS SCIENCE Melt temperature METHANOL MORPHOLOGY NMR NMR SPECTROMETERS Nuclear magnetic resonance Organic chemistry Original Paper PH VALUE Polycondensation reactions Polyester resins POLYESTERS Polymer Sciences Polymers SCANNING ELECTRON MICROSCOPY SURFACE COATING Surgical implants SYNTHESIS TAMOXIFEN Tamoxifen citrate Temperature effects TITANIUM TOXICITY TRANSITION TEMPERATURE Transition temperatures Tumor cell lines X-RAY DIFFRACTION
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