Synthesis of novel α-aminophosphonates under microwave irradiation, biological evaluation as antiproliferative agents and apoptosis inducers

The synthesis of two series of α-aminophosphonates was achieved by Microwave Irradiation (MW), using the one-pot Kabachnik–Fields reaction. Based on a green chemistry approach, the reactions were carried out using ethanol as the only solvent and without any catalyst, and short reaction times (20–40 ...

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Veröffentlicht in:Medicinal chemistry research 2019-11, Vol.28 (11), p.2067-2078
Hauptverfasser: Loredo-Calderón, Erika L., Velázquez-Martínez, Carlos A., Ramírez-Cabrera, Mónica A., Hernández-Fernández, Eugenio, Rivas-Galindo, Verónica M., Arredondo Espinoza, Eder, López-Cortina, Susana T.
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Sprache:eng
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