The distribution of complexes {sup 69m}ZnL{sup 1}Cl{sub 2}, [{sup 69m}Zn(L{sup 2}){sub 2}]Cl{sub 2}, and [{sup 69m}Zn(L{sup 2}){sub 2}]Sal{sub 2} (L{sup 1} is N-(5,6-dihydro-4H-1,3-thiazin-2-yl)benzamide, L{sup 2} is 2-aminopyrimidine, Sal is a salicylate ion) in vivo in mice

The distribution of complexes of thiazine and pyrimidine derivatives possessing antileukemic activity and labeled with radionuclide {sup 69m}Zn in the organs of mice and its rate of excretion were studied. A solution of ZnCl{sub 2} was used for comparison. An increase in the time of excretion of the drug from the body and a decrease of its penetration into the brain in the presence of a salicylate ion were observed.