Aging-associated changes in oxidative stress, cell proliferation, and apoptosis are prevented in the prostate of transgenic rats overexpressing regucalcin

Regucalcin (RGN) is a calcium (Ca2+ )-binding protein that displays a characteristic downregulated expression with aging in several tissues. Besides its role in regulating intracellular Ca2+ homeostasis, RGN has been associated with the control of oxidative stress, cell proliferation, and apoptosis....

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Veröffentlicht in:	Translational research : the journal of laboratory and clinical medicine 2015-12, Vol.166 (6), p.693-705
Hauptverfasser:	Vaz, Cátia V, Marques, Ricardo, Maia, Cláudio J, Socorro, Sílvia
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Animals Apoptosis Calcium-Binding Proteins - metabolism Cell Proliferation Internal Medicine Intracellular Signaling Peptides and Proteins - metabolism Male Organ Size Oxidative Stress Prostate - metabolism Prostate - pathology Rats Rats, Sprague-Dawley Rats, Transgenic
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