Structural insights into phospholipase D function

Phospholipase D (PLD) and its metabolic active product phosphatidic acid (PA) engage in a wide range of physiopathologic processes in the cell. PLDs have been considered as a potential and promising drug target. Recently, the crystal structures of PLDs in mammalian and plant have been solved at atom...

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Veröffentlicht in:	Progress in lipid research 2021-01, Vol.81 (C), p.101070, Article 101070
Hauptverfasser:	Yao, Yuanfa, Li, Jianxu, Lin, Yinyan, Zhou, Jiaqiang, Zhang, Peng, Xu, Yingke
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Crystal structure HKD domain Phosphatidic acid Phosphatidic Acids Phospholipase D Plants Protein Isoforms
Online-Zugang:	Volltext
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