High expression of Ki-67 acts a poor prognosis indicator in locally advanced nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC) is a common head and neck malignancy in Southern China and Southeast Asia compared with Western countries. The standard treatment for NPC is radiotherapy. However, radioresistance remains a serious obstacle to satisfactory treatment, it can cause local recurrence and d...

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Veröffentlicht in:	Biochemical and biophysical research communications 2017-12, Vol.494 (1-2), p.390-396
Hauptverfasser:	Zhao, Yajie, Shen, Lin, Huang, Xinqiong, Jing, Di, Huang, David, Fu, Jun, Li, Zhanzhan, Zhang, Guangying, Shen, Liangfang
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Adolescent Adult Aged Aged, 80 and over Antibodies, Monoclonal, Humanized - therapeutic use Antineoplastic Agents - therapeutic use Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Carcinoma - diagnosis Carcinoma - genetics Carcinoma - mortality Carcinoma - therapy CARCINOMAS Cetuximab - therapeutic use CHINA Female Gamma Rays - therapeutic use HEAD HOSPITALS Humans Immunohistochemistry Ki-67 Ki-67 Antigen - genetics Ki-67 Antigen - metabolism Local advanced nasopharyngeal carcinoma Male METASTASES Middle Aged MULTIVARIATE ANALYSIS Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms - diagnosis Nasopharyngeal Neoplasms - genetics Nasopharyngeal Neoplasms - mortality Nasopharyngeal Neoplasms - therapy NECK Neoplasm Staging PATIENTS POTASSIUM IODIDES Prognosis Radiation resistance RADIOSENSITIVITY RADIOTHERAPY Retrospective Studies REVIEWS Survival Analysis
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