RAP80 binds p32 to preserve the functional integrity of mitochondria

RAP80, a member of the BRCA1-A complex, is a well-known crucial regulator of cell cycle checkpoint and DNA damage repair in the nucleus. However, it is still unclear whether Rap80 localizes to another region outside the nucleus and plays different roles with its partners. Here, we found mitochondria...

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Veröffentlicht in:	Biochemical and biophysical research communications 2017-10, Vol.492 (3), p.441-446
Hauptverfasser:	Chung, Hee Jin, Korm, Sovannarith, Lee, Se-in, Phorl, Sophors, Noh, Solhee, Han, Miae, Naskar, Rema, Kim, Hongtae, Lee, Joo-Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES ARGININE Carrier Proteins - genetics Carrier Proteins - metabolism CELL CYCLE Cells, Cultured DNA DNA DAMAGES DNA-Binding Proteins GLYCOLYSIS Histone Chaperones Humans HYBRIDIZATION Metabolism MITOCHONDRIA Mitochondria - metabolism Mitochondrial Proteins - genetics Mitochondrial Proteins - metabolism Mutation Nuclear Proteins - deficiency Nuclear Proteins - genetics Nuclear Proteins - metabolism Oxygen consumption p32 PROTEINS RAP80 YEASTS
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