Differences in toxicity of anionic and cationic PAMAM and PPI dendrimers in zebrafish embryos and cancer cell lines

Dendrimers are an emerging class of polymeric nanoparticles with beneficial biomedical applications like early diagnostics, in vitro gene transfection or controlled drug delivery. However, the potential toxic impact of exposure on human health or the environment is often inadequately defined. Thus,...

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Veröffentlicht in:Toxicology and applied pharmacology 2016-08, Vol.305, p.83-92
Hauptverfasser: Bodewein, Lambert, Schmelter, Frank, Di Fiore, Stefano, Hollert, Henner, Fischer, Rainer, Fenske, Martina
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Sprache:eng
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