Predictors of Liver Toxicity Following Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma

To identify risk factors associated with a decline in liver function after stereotactic body radiation therapy (SBRT) for hepatocellular carcinoma. Data were analyzed from patients with hepatocellular carcinoma treated on clinical trials of 6-fraction SBRT. Liver toxicity was defined as an increase...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2017-04, Vol.97 (5), p.939-946
Hauptverfasser:	Velec, Michael, Haddad, Carol R., Craig, Tim, Wang, Lisa, Lindsay, Patricia, Brierley, James, Brade, Anthony, Ringash, Jolie, Wong, Rebecca, Kim, John, Dawson, Laura A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Carcinoma, Hepatocellular - diagnosis Carcinoma, Hepatocellular - epidemiology Carcinoma, Hepatocellular - radiotherapy CLINICAL TRIALS Dose-Response Relationship, Radiation Female GY RANGE 01-10 GY RANGE 10-100 HEPATOMAS Humans LIVER Liver Diseases - diagnosis Liver Diseases - epidemiology Liver Diseases - prevention & control Liver Neoplasms - diagnosis Liver Neoplasms - epidemiology Liver Neoplasms - radiotherapy Male Middle Aged MULTIVARIATE ANALYSIS Ontario PATIENTS Prevalence RADIATION DOSES RADIATION HAZARDS Radiation Injuries - diagnosis Radiation Injuries - epidemiology Radiation Injuries - prevention & control RADIOLOGY AND NUCLEAR MEDICINE Radiosurgery RADIOTHERAPY Radiotherapy Dosage Risk Assessment - methods TOXICITY Treatment Outcome VEINS
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