Efficacy and Safety of Adjuvant Proton Therapy Combined With Surgery for Chondrosarcoma of the Skull Base: A Retrospective, Population-Based Study

Purpose Chondrosarcoma is a rare malignant tumor of the cartilage affecting young adults. Surgery, followed by charged-particle irradiation, is considered the reference standard for the treatment of patients with grade I to II skull base chondrosarcoma. The present study was conducted to assess the...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2016-05, Vol.95 (1), p.312-321
Hauptverfasser:	Feuvret, Loïc, MD, Bracci, Stefano, MD, Calugaru, Valentin, MD, PhD, Bolle, Stéphanie, MD, Mammar, Hamid, MD, De Marzi, Ludovic, PhD, Bresson, Damien, MD, Habrand, Jean-Louis, MD, PhD, Mazeron, Jean-Jacques, MD, PhD, Dendale, Rémi, MD, Noël, Georges, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Child Chondrosarcoma - mortality Chondrosarcoma - pathology Chondrosarcoma - radiotherapy Chondrosarcoma - surgery Follow-Up Studies GY RANGE 10-100 Hematology, Oncology and Palliative Medicine Humans Middle Aged MULTIVARIATE ANALYSIS Neoplasm Recurrence, Local Organ Sparing Treatments Organs at Risk PATIENTS Photons - therapeutic use PROTON BEAMS Proton Therapy - adverse effects Proton Therapy - methods RADIATION HAZARDS Radiology RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Radiotherapy, Adjuvant - adverse effects Radiotherapy, Adjuvant - methods Relative Biological Effectiveness Retrospective Studies SARCOMAS SKELETAL DISEASES SKULL Skull Base Neoplasms - mortality Skull Base Neoplasms - pathology Skull Base Neoplasms - radiotherapy Skull Base Neoplasms - surgery SURGERY Survival Rate Time Factors Tumor Burden
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