Transcatheter Arterial Embolization with N-Butyl-2-Cyanoacrylate in the Management of Spontaneous Hematomas
Introduction Spontaneous hematoma refractory to conservative management is a potentially serious condition that requires prompt diagnosis and intervention. The purpose of this study was to evaluate the performance of computed tomography (CT) in the treatment planning and to report the effectiveness...
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description | Introduction
Spontaneous hematoma refractory to conservative management is a potentially serious condition that requires prompt diagnosis and intervention. The purpose of this study was to evaluate the performance of computed tomography (CT) in the treatment planning and to report the effectiveness of transcatheter embolization with
N
-butyl-2-cyanoacrylate (NBCA).
Materials and Methods
Forty-one interventions in 38 patients within a 12-year period were evaluated. CT and angiograms were reviewed for the location of the hematoma, the presence of extravasation, and the correlation of CT and angiography findings.
Results
Arterial extravasation was present on 34/39 CT scans. Angiograms confirmed the CT scans in 29 cases. Angiograms revealed extravasation in four cases which CT showed venous bleeding (
n
= 2) or no bleeding (
n
= 2). Five patients with arterial and 1 patient with venous extravasation on CT images had no extravasation on angiograms. Embolization was performed to all arteries with extravasation on angiograms. Empiric embolization of the corresponding artery on the CT was performed when there was no extravasation on angiograms. Embolization procedures were performed with 15 % NBCA diluted with iodized oil. Technical success was achieved in 40/41 (97.6 %) interventions. Clinical success was achieved in 35 patients with a single, in 1 patient with 2, and in 1 patient with 3 interventions. No complications related to embolization procedure occurred. None of the patients died due to a progression of the hematoma.
Conclusion
NBCA is an effective and safe embolic agent to treat hematoma refractory to conservative management. Contrast-enhanced CT may provide faster and more effective intervention.
Level of Evidence III
Retrospective. |
doi_str_mv | 10.1007/s00270-016-1463-6 |
format | Article |
fullrecord | <record><control><sourceid>proquest_osti_</sourceid><recordid>TN_cdi_osti_scitechconnect_22645362</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1859496125</sourcerecordid><originalsourceid>FETCH-LOGICAL-c476t-479acff2c46ea9882e680d318e94f1530acd8676ed492119ae6e2519be607bb3</originalsourceid><addsrcrecordid>eNqNkc1u1DAUhS0EokPhAdggS2zYGHwd_yTLMioUqT8LZsHOcjw3nZTEHmxHaHh6MkopbCqxsRf-zrnX-gh5Dfw9cG4-ZM6F4YyDZiB1xfQTsgJZCcZr_e0pWXEwkoFScEJe5HzHOahaqOfkRBgttRLVinzfJBeyd2WHBRM9S_PZu4Gej20c-l-u9DHQn33Z0Wv2cSqHgQm2PrgQnU-HwRWkfaBzmF654G5xxFBo7OjXfQzFBYxTphc4uhJHl1-SZ50bMr66v0_J5tP5Zn3BLm8-f1mfXTIvjS5Mmsb5rhNeanRNXQvUNd9WUGMjO1AVd35ba6NxKxsB0DjUKBQ0LWpu2rY6JW-X2phLb7PvC_qdjyGgL1YILVWlxUy9W6h9ij8mzMWOffY4DMvWFmrVyEaDUP-DgjDCGP539gN6F6cU5t8eKa4bqISZKVgon2LOCTu7T_3o0sECt0ezdjFrZ7P2aNbqOfPmvnlqR9w-JP6onAGxAHl-CreY_hn9aOtv6wKtFQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1850691327</pqid></control><display><type>article</type><title>Transcatheter Arterial Embolization with N-Butyl-2-Cyanoacrylate in the Management of Spontaneous Hematomas</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Ozyer, Umut</creator><creatorcontrib>Ozyer, Umut</creatorcontrib><description>Introduction
Spontaneous hematoma refractory to conservative management is a potentially serious condition that requires prompt diagnosis and intervention. The purpose of this study was to evaluate the performance of computed tomography (CT) in the treatment planning and to report the effectiveness of transcatheter embolization with
N
-butyl-2-cyanoacrylate (NBCA).
Materials and Methods
Forty-one interventions in 38 patients within a 12-year period were evaluated. CT and angiograms were reviewed for the location of the hematoma, the presence of extravasation, and the correlation of CT and angiography findings.
Results
Arterial extravasation was present on 34/39 CT scans. Angiograms confirmed the CT scans in 29 cases. Angiograms revealed extravasation in four cases which CT showed venous bleeding (
n
= 2) or no bleeding (
n
= 2). Five patients with arterial and 1 patient with venous extravasation on CT images had no extravasation on angiograms. Embolization was performed to all arteries with extravasation on angiograms. Empiric embolization of the corresponding artery on the CT was performed when there was no extravasation on angiograms. Embolization procedures were performed with 15 % NBCA diluted with iodized oil. Technical success was achieved in 40/41 (97.6 %) interventions. Clinical success was achieved in 35 patients with a single, in 1 patient with 2, and in 1 patient with 3 interventions. No complications related to embolization procedure occurred. None of the patients died due to a progression of the hematoma.
Conclusion
NBCA is an effective and safe embolic agent to treat hematoma refractory to conservative management. Contrast-enhanced CT may provide faster and more effective intervention.
Level of Evidence III
Retrospective.</description><identifier>ISSN: 0174-1551</identifier><identifier>EISSN: 1432-086X</identifier><identifier>DOI: 10.1007/s00270-016-1463-6</identifier><identifier>PMID: 27646523</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>ADMINISTRATIVE PROCEDURES ; Adult ; Aged ; Aged, 80 and over ; Angiography ; ARTERIES ; BIOMEDICAL RADIOGRAPHY ; Cardiology ; Clinical Investigation ; COMPUTERIZED TOMOGRAPHY ; CORRELATIONS ; DIAGNOSIS ; Embolization, Therapeutic - methods ; Enbucrilate - therapeutic use ; Female ; Hematoma - diagnostic imaging ; Hematoma - therapy ; HEMATOMAS ; Humans ; Imaging ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Nuclear Medicine ; PATIENTS ; PLANNING ; Radiology ; RADIOLOGY AND NUCLEAR MEDICINE ; Retrospective Studies ; REVIEWS ; Tomography, X-Ray Computed ; Treatment Outcome ; Ultrasound ; VASCULAR DISEASES ; Young Adult</subject><ispartof>Cardiovascular and interventional radiology, 2017-01, Vol.40 (1), p.41-49</ispartof><rights>Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2016</rights><rights>CardioVascular and Interventional Radiology is a copyright of Springer, 2017.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c476t-479acff2c46ea9882e680d318e94f1530acd8676ed492119ae6e2519be607bb3</citedby><cites>FETCH-LOGICAL-c476t-479acff2c46ea9882e680d318e94f1530acd8676ed492119ae6e2519be607bb3</cites><orcidid>0000-0002-4300-009X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00270-016-1463-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00270-016-1463-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,780,784,885,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27646523$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/22645362$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Ozyer, Umut</creatorcontrib><title>Transcatheter Arterial Embolization with N-Butyl-2-Cyanoacrylate in the Management of Spontaneous Hematomas</title><title>Cardiovascular and interventional radiology</title><addtitle>Cardiovasc Intervent Radiol</addtitle><addtitle>Cardiovasc Intervent Radiol</addtitle><description>Introduction
Spontaneous hematoma refractory to conservative management is a potentially serious condition that requires prompt diagnosis and intervention. The purpose of this study was to evaluate the performance of computed tomography (CT) in the treatment planning and to report the effectiveness of transcatheter embolization with
N
-butyl-2-cyanoacrylate (NBCA).
Materials and Methods
Forty-one interventions in 38 patients within a 12-year period were evaluated. CT and angiograms were reviewed for the location of the hematoma, the presence of extravasation, and the correlation of CT and angiography findings.
Results
Arterial extravasation was present on 34/39 CT scans. Angiograms confirmed the CT scans in 29 cases. Angiograms revealed extravasation in four cases which CT showed venous bleeding (
n
= 2) or no bleeding (
n
= 2). Five patients with arterial and 1 patient with venous extravasation on CT images had no extravasation on angiograms. Embolization was performed to all arteries with extravasation on angiograms. Empiric embolization of the corresponding artery on the CT was performed when there was no extravasation on angiograms. Embolization procedures were performed with 15 % NBCA diluted with iodized oil. Technical success was achieved in 40/41 (97.6 %) interventions. Clinical success was achieved in 35 patients with a single, in 1 patient with 2, and in 1 patient with 3 interventions. No complications related to embolization procedure occurred. None of the patients died due to a progression of the hematoma.
Conclusion
NBCA is an effective and safe embolic agent to treat hematoma refractory to conservative management. Contrast-enhanced CT may provide faster and more effective intervention.
Level of Evidence III
Retrospective.</description><subject>ADMINISTRATIVE PROCEDURES</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Angiography</subject><subject>ARTERIES</subject><subject>BIOMEDICAL RADIOGRAPHY</subject><subject>Cardiology</subject><subject>Clinical Investigation</subject><subject>COMPUTERIZED TOMOGRAPHY</subject><subject>CORRELATIONS</subject><subject>DIAGNOSIS</subject><subject>Embolization, Therapeutic - methods</subject><subject>Enbucrilate - therapeutic use</subject><subject>Female</subject><subject>Hematoma - diagnostic imaging</subject><subject>Hematoma - therapy</subject><subject>HEMATOMAS</subject><subject>Humans</subject><subject>Imaging</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Nuclear Medicine</subject><subject>PATIENTS</subject><subject>PLANNING</subject><subject>Radiology</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>Retrospective Studies</subject><subject>REVIEWS</subject><subject>Tomography, X-Ray Computed</subject><subject>Treatment Outcome</subject><subject>Ultrasound</subject><subject>VASCULAR DISEASES</subject><subject>Young Adult</subject><issn>0174-1551</issn><issn>1432-086X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNkc1u1DAUhS0EokPhAdggS2zYGHwd_yTLMioUqT8LZsHOcjw3nZTEHmxHaHh6MkopbCqxsRf-zrnX-gh5Dfw9cG4-ZM6F4YyDZiB1xfQTsgJZCcZr_e0pWXEwkoFScEJe5HzHOahaqOfkRBgttRLVinzfJBeyd2WHBRM9S_PZu4Gej20c-l-u9DHQn33Z0Wv2cSqHgQm2PrgQnU-HwRWkfaBzmF654G5xxFBo7OjXfQzFBYxTphc4uhJHl1-SZ50bMr66v0_J5tP5Zn3BLm8-f1mfXTIvjS5Mmsb5rhNeanRNXQvUNd9WUGMjO1AVd35ba6NxKxsB0DjUKBQ0LWpu2rY6JW-X2phLb7PvC_qdjyGgL1YILVWlxUy9W6h9ij8mzMWOffY4DMvWFmrVyEaDUP-DgjDCGP539gN6F6cU5t8eKa4bqISZKVgon2LOCTu7T_3o0sECt0ezdjFrZ7P2aNbqOfPmvnlqR9w-JP6onAGxAHl-CreY_hn9aOtv6wKtFQ</recordid><startdate>20170101</startdate><enddate>20170101</enddate><creator>Ozyer, Umut</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>7U7</scope><scope>C1K</scope><scope>OTOTI</scope><orcidid>https://orcid.org/0000-0002-4300-009X</orcidid></search><sort><creationdate>20170101</creationdate><title>Transcatheter Arterial Embolization with N-Butyl-2-Cyanoacrylate in the Management of Spontaneous Hematomas</title><author>Ozyer, Umut</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c476t-479acff2c46ea9882e680d318e94f1530acd8676ed492119ae6e2519be607bb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>ADMINISTRATIVE PROCEDURES</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Angiography</topic><topic>ARTERIES</topic><topic>BIOMEDICAL RADIOGRAPHY</topic><topic>Cardiology</topic><topic>Clinical Investigation</topic><topic>COMPUTERIZED TOMOGRAPHY</topic><topic>CORRELATIONS</topic><topic>DIAGNOSIS</topic><topic>Embolization, Therapeutic - methods</topic><topic>Enbucrilate - therapeutic use</topic><topic>Female</topic><topic>Hematoma - diagnostic imaging</topic><topic>Hematoma - therapy</topic><topic>HEMATOMAS</topic><topic>Humans</topic><topic>Imaging</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Nuclear Medicine</topic><topic>PATIENTS</topic><topic>PLANNING</topic><topic>Radiology</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Retrospective Studies</topic><topic>REVIEWS</topic><topic>Tomography, X-Ray Computed</topic><topic>Treatment Outcome</topic><topic>Ultrasound</topic><topic>VASCULAR DISEASES</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ozyer, Umut</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>OSTI.GOV</collection><jtitle>Cardiovascular and interventional radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ozyer, Umut</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Transcatheter Arterial Embolization with N-Butyl-2-Cyanoacrylate in the Management of Spontaneous Hematomas</atitle><jtitle>Cardiovascular and interventional radiology</jtitle><stitle>Cardiovasc Intervent Radiol</stitle><addtitle>Cardiovasc Intervent Radiol</addtitle><date>2017-01-01</date><risdate>2017</risdate><volume>40</volume><issue>1</issue><spage>41</spage><epage>49</epage><pages>41-49</pages><issn>0174-1551</issn><eissn>1432-086X</eissn><abstract>Introduction
Spontaneous hematoma refractory to conservative management is a potentially serious condition that requires prompt diagnosis and intervention. The purpose of this study was to evaluate the performance of computed tomography (CT) in the treatment planning and to report the effectiveness of transcatheter embolization with
N
-butyl-2-cyanoacrylate (NBCA).
Materials and Methods
Forty-one interventions in 38 patients within a 12-year period were evaluated. CT and angiograms were reviewed for the location of the hematoma, the presence of extravasation, and the correlation of CT and angiography findings.
Results
Arterial extravasation was present on 34/39 CT scans. Angiograms confirmed the CT scans in 29 cases. Angiograms revealed extravasation in four cases which CT showed venous bleeding (
n
= 2) or no bleeding (
n
= 2). Five patients with arterial and 1 patient with venous extravasation on CT images had no extravasation on angiograms. Embolization was performed to all arteries with extravasation on angiograms. Empiric embolization of the corresponding artery on the CT was performed when there was no extravasation on angiograms. Embolization procedures were performed with 15 % NBCA diluted with iodized oil. Technical success was achieved in 40/41 (97.6 %) interventions. Clinical success was achieved in 35 patients with a single, in 1 patient with 2, and in 1 patient with 3 interventions. No complications related to embolization procedure occurred. None of the patients died due to a progression of the hematoma.
Conclusion
NBCA is an effective and safe embolic agent to treat hematoma refractory to conservative management. Contrast-enhanced CT may provide faster and more effective intervention.
Level of Evidence III
Retrospective.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>27646523</pmid><doi>10.1007/s00270-016-1463-6</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-4300-009X</orcidid><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; SpringerNature Journals |
subjects | ADMINISTRATIVE PROCEDURES Adult Aged Aged, 80 and over Angiography ARTERIES BIOMEDICAL RADIOGRAPHY Cardiology Clinical Investigation COMPUTERIZED TOMOGRAPHY CORRELATIONS DIAGNOSIS Embolization, Therapeutic - methods Enbucrilate - therapeutic use Female Hematoma - diagnostic imaging Hematoma - therapy HEMATOMAS Humans Imaging Male Medicine Medicine & Public Health Middle Aged Nuclear Medicine PATIENTS PLANNING Radiology RADIOLOGY AND NUCLEAR MEDICINE Retrospective Studies REVIEWS Tomography, X-Ray Computed Treatment Outcome Ultrasound VASCULAR DISEASES Young Adult |
title | Transcatheter Arterial Embolization with N-Butyl-2-Cyanoacrylate in the Management of Spontaneous Hematomas |
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