Age- and sex-related differences of organic anion-transporting polypeptide gene expression in livers of rats

Organic anion-transporting polypeptides (Oatps) play important roles in transporting endogenous substances and xenobiotics into the liver and are implicated in drug-drug interactions. Many factors could influence their expression and result in alterations in drug disposition, efficacy and toxicity....

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Veröffentlicht in:Toxicology and applied pharmacology 2014-10, Vol.280 (2), p.370-377
Hauptverfasser: Hou, Wei-Yu, Xu, Shang-Fu, Zhu, Qiong-Ni, Lu, Yuan-Fu, Cheng, Xing-Guo, Liu, Jie
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Sprache:eng
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