Random Forests to Predict Rectal Toxicity Following Prostate Cancer Radiation Therapy

Purpose To propose a random forest normal tissue complication probability (RF-NTCP) model to predict late rectal toxicity following prostate cancer radiation therapy, and to compare its performance to that of classic NTCP models. Methods and Materials Clinical data and dose-volume histograms (DVH) w...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2014-08, Vol.89 (5), p.1024-1031
Hauptverfasser:	Ospina, Juan D., PhD, Zhu, Jian, PhD, Chira, Ciprian, MD, Bossi, Alberto, MD, PhD, Delobel, Jean B., MD, Beckendorf, Véronique, MD, PhD, Dubray, Bernard, MD, PhD, Lagrange, Jean-Léon, MD, PhD, Correa, Juan C., PhD, Simon, Antoine, PhD, Acosta, Oscar, PhD, de Crevoisier, Renaud, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Aged Aged, 80 and over ANTICOAGULANTS Anticoagulants - administration & dosage Anticoagulants - adverse effects Area Under Curve Gastrointestinal Hemorrhage - epidemiology Gastrointestinal Hemorrhage - etiology Hematology, Oncology and Palliative Medicine Humans Male Middle Aged Models, Statistical NEOPLASMS PATIENTS Probability Prospective Studies PROSTATE Prostatic Neoplasms - radiotherapy RADIATION DOSES Radiation Injuries - complications Radiation Injuries - epidemiology Radiology RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Radiotherapy Dosage Radiotherapy, Conformal - adverse effects Radiotherapy, Conformal - methods Radiotherapy, Conformal - statistics & numerical data Radiotherapy, Image-Guided Radiotherapy, Intensity-Modulated RECTUM Rectum - radiation effects Retrospective Studies ROC Curve TOXICITY
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