Similar Survival for Patients Undergoing Reduced-Intensity Total Body Irradiation (TBI) Versus Myeloablative TBI as Conditioning for Allogeneic Transplant in Acute Leukemia

Purpose Hematopoietic stem cell transplantation (HSCT) is the mainstay of treatment for adults with acute leukemia. Total body irradiation (TBI) remains an important part of the conditioning regimen for HCST. For those patients unable to tolerate myeloablative TBI (mTBI), reduced intensity TBI (riTB...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2014-06, Vol.89 (2), p.360-369
Hauptverfasser:	Mikell, John L., MD, Waller, Edmund K., MD, PhD, Switchenko, Jeffrey M., PhD, Rangaraju, Sravanti, MBBS, Ali, Zahir, MS, Graiser, Michael, PhD, Hall, William A., MD, Langston, Amelia A., MD, Esiashvili, Natia, MD, Khoury, H. Jean, MD, Khan, Mohammad K., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult ADULTS Age Factors Allografts COMPARATIVE EVALUATIONS DIAGNOSIS Disease-Free Survival Female Hematology, Oncology and Palliative Medicine Humans Immunosuppressive Agents - therapeutic use Karnofsky Performance Status Length of Stay LEUKEMIA Leukemia - mortality Leukemia - therapy Leukemia, Myeloid, Acute - mortality Leukemia, Myeloid, Acute - therapy Male Middle Aged Neoplasm Recurrence, Local PATIENTS Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy Radiology RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Retrospective Studies REVIEWS STEM CELLS Survival Analysis SURVIVAL TIME TOXICITY Transplantation Conditioning - adverse effects Transplantation Conditioning - methods Transplantation Conditioning - mortality WHOLE-BODY IRRADIATION Whole-Body Irradiation - adverse effects Whole-Body Irradiation - methods Whole-Body Irradiation - mortality
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