Nanomechanical and topographical imaging of living cells by atomic force microscopy with colloidal probes

Atomic Force Microscopy (AFM) has a great potential as a tool to characterize mechanical and morphological properties of living cells; these properties have been shown to correlate with cells' fate and patho-physiological state in view of the development of novel early-diagnostic strategies. Al...

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Veröffentlicht in:	Review of scientific instruments 2015-03, Vol.86 (3), p.033705-033705
Hauptverfasser:	Puricelli, Luca, Galluzzi, Massimiliano, Schulte, Carsten, Podestà, Alessandro, Milani, Paolo
Format:	Artikel
Sprache:	eng
Schlagworte:	ACCURACY Animals ATOMIC FORCE MICROSCOPY Biomechanical Phenomena Cell Adhesion Cell Line, Tumor Cells (biology) Colloids CORRECTIONS Diagnostic systems DRUGS Elastic Modulus Elastic properties ELASTICITY GEOMETRY Humans INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY MAPPING Mechanical analysis Mechanical measurement Microscopes Microscopy Microscopy, Atomic Force - instrumentation Microscopy, Atomic Force - methods MICROTUBULES Modulus of elasticity Morphology PC12 Cells - cytology PC12 Cells - physiology PROBES Rats Scientific apparatus & instruments Single-Cell Analysis - instrumentation Single-Cell Analysis - methods SPATIAL RESOLUTION SPHERICAL CONFIGURATION THICKNESS Tips
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