Mobilization of Viable Tumor Cells Into the Circulation During Radiation Therapy

Purpose To determine whether radiation therapy (RT) could mobilize viable tumor cells into the circulation of non-small cell lung cancer (NSCLC) patients. Methods and Materials We enumerated circulating tumor cells (CTCs) by fluorescence microscopy of blood samples immunostained with conventional CT...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2014-02, Vol.88 (2), p.395-403
Hauptverfasser:	Martin, Olga A., PhD, Anderson, Robin L., PhD, Russell, Prudence A., MD, Ashley Cox, R., FRCR, Ivashkevich, Alesia, PhD, Swierczak, Agnieszka, PhD, Doherty, Judy P., BSc (Hons), Jacobs, Daphne H.M., BSc, Smith, Jai, BSc (Hons), Siva, Shankar, FRANZCR, Daly, Patricia E., FFRRCSI, Ball, David L., FRANZCR, Martin, Roger F., PhD, MacManus, Michael P., FRANZCR
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over BIOLOGICAL MARKERS Biomarkers, Tumor - analysis BLOOD Carcinoma, Non-Small-Cell Lung - blood Carcinoma, Non-Small-Cell Lung - pathology Carcinoma, Non-Small-Cell Lung - radiotherapy Cell Proliferation - radiation effects Cell Survival DNA DNA Breaks, Double-Stranded FLUORESCENCE Hematology, Oncology and Palliative Medicine Histones - analysis Humans Lung Neoplasms - blood Lung Neoplasms - pathology Lung Neoplasms - radiotherapy LUNGS Microscopy, Fluorescence Middle Aged NEOPLASMS Neoplastic Cells, Circulating - pathology Neoplastic Cells, Circulating - radiation effects PATIENTS Radiology RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY STRAND BREAKS TUMOR CELLS
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