Cadmium, lead and mercury exposure in non smoking pregnant women
Recent literature suggests that exposure to low concentrations of heavy metals may affect both maternal and child health. This study aimed to determine the biological heavy metals concentrations of pregnant women as well as environmental and dietary factors that may influence exposure concentrations...
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| Veröffentlicht in: | Environmental research 2013-10, Vol.126, p.118-124 |
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| creator | Hinwood, A.L. Callan, A.C. Ramalingam, M. Boyce, M. Heyworth, J. McCafferty, P. Odland, J.Ø. |
| description | Recent literature suggests that exposure to low concentrations of heavy metals may affect both maternal and child health. This study aimed to determine the biological heavy metals concentrations of pregnant women as well as environmental and dietary factors that may influence exposure concentrations. One hundred and seventy three pregnant women were recruited from Western Australia, each providing a sample of blood, first morning void urine, residential soil, dust and drinking water samples. Participants also completed a questionnaire which included a food frequency component. All biological and environmental samples were analysed for heavy metals using ICP-MS. Biological and environmental concentrations of lead and mercury were generally low (Median Pb Drinking Water (DW) 0.04µg/L; Pb soil |
| doi_str_mv | 10.1016/j.envres.2013.07.005 |
| format | Article |
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•Biological heavy metals concentrations in women in their 3rd trimester of pregnancy.•Exposure assessment including environmental, lifestyle and activity data.•Urinary cadmium concentrations were elevated in this group of pregnant women.•Blood lead and mercury concentrations were below recommended biological guideline values.]]></description><identifier>ISSN: 0013-9351</identifier><identifier>EISSN: 1096-0953</identifier><identifier>DOI: 10.1016/j.envres.2013.07.005</identifier><identifier>PMID: 23890969</identifier><identifier>CODEN: ENVRAL</identifier><language>eng</language><publisher>Amsterdam: Elsevier Inc</publisher><subject>60 APPLIED LIFE SCIENCES ; ABUNDANCE ; Adult ; Biological ; Biological and medical sciences ; BIOLOGICAL MARKERS ; Biomarkers ; BLOOD ; CADMIUM ; Chemical and industrial products toxicology. Toxic occupational diseases ; CONCENTRATION RATIO ; CREATININE ; Cross-Sectional Studies ; DIET ; DRINKING WATER ; Dust ; DUSTS ; ECOLOGICAL CONCENTRATION ; Environment ; Environmental Exposure - statistics & numerical data ; ENVIRONMENTAL MATERIALS ; Exposure ; Female ; FOLIC ACID ; HEAVY METALS ; Humans ; ICP MASS SPECTROSCOPY ; IRON ; LEAD ; Lead (metal) ; Linear Models ; Maternal ; Mathematical models ; Medical sciences ; MERCURY ; Mercury (metal) ; Metals and various inorganic compounds ; Metals, Heavy - blood ; Metals, Heavy - urine ; PETROLEUM RESIDUES ; PREGNANCY ; SMOKES ; SOCIO-ECONOMIC FACTORS ; SOILS ; Toxicology ; URINE ; WESTERN AUSTRALIA ; Young Adult</subject><ispartof>Environmental research, 2013-10, Vol.126, p.118-124</ispartof><rights>2013</rights><rights>2014 INIST-CNRS</rights><rights>Crown Copyright © 2013. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c552t-151fe3f84a7f377742e095058b35373bef63dff36e69911d64a2e108785cad133</citedby><cites>FETCH-LOGICAL-c552t-151fe3f84a7f377742e095058b35373bef63dff36e69911d64a2e108785cad133</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0013935113001217$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27868278$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23890969$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/22246954$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Hinwood, A.L.</creatorcontrib><creatorcontrib>Callan, A.C.</creatorcontrib><creatorcontrib>Ramalingam, M.</creatorcontrib><creatorcontrib>Boyce, M.</creatorcontrib><creatorcontrib>Heyworth, J.</creatorcontrib><creatorcontrib>McCafferty, P.</creatorcontrib><creatorcontrib>Odland, J.Ø.</creatorcontrib><title>Cadmium, lead and mercury exposure in non smoking pregnant women</title><title>Environmental research</title><addtitle>Environ Res</addtitle><description><![CDATA[Recent literature suggests that exposure to low concentrations of heavy metals may affect both maternal and child health. This study aimed to determine the biological heavy metals concentrations of pregnant women as well as environmental and dietary factors that may influence exposure concentrations. One hundred and seventy three pregnant women were recruited from Western Australia, each providing a sample of blood, first morning void urine, residential soil, dust and drinking water samples. Participants also completed a questionnaire which included a food frequency component. All biological and environmental samples were analysed for heavy metals using ICP-MS. Biological and environmental concentrations of lead and mercury were generally low (Median Pb Drinking Water (DW) 0.04µg/L; Pb soil <3.0µg/g; Pb dust 16.5µg/g; Pb blood 3.67µg/L; Pb urine 0.55; µg/L Hg DW <0.03; Hg soil <1.0µg/g; Hg dust <1.0µg/g; Hg blood 0.46µg/L; Hg urine <0.40µg/L). Cadmium concentrations were low in environmental samples (Median CdDW 0.02µg/L; Cdsoil <0.30ug/g; Cddust <0.30) but elevated in urine samples (Median 0.55µg/L, creatinine corrected 0.70µg/g (range <0.2–7.06µg/g creatinine) compared with other studies of pregnant women. Predictors of increased biological metals concentrations in regression models for blood cadmium were residing in the Great Southern region of Western Australia and not using iron/folic acid supplements and for urinary cadmium was having lower household annual income. However, these factors explained little of the variation in respective biological metals concentrations. The importance of establishing factors that influence low human exposure concentrations is becoming critical in efforts to reduce exposures and hence the potential for adverse health effects.
•Biological heavy metals concentrations in women in their 3rd trimester of pregnancy.•Exposure assessment including environmental, lifestyle and activity data.•Urinary cadmium concentrations were elevated in this group of pregnant women.•Blood lead and mercury concentrations were below recommended biological guideline values.]]></description><subject>60 APPLIED LIFE SCIENCES</subject><subject>ABUNDANCE</subject><subject>Adult</subject><subject>Biological</subject><subject>Biological and medical sciences</subject><subject>BIOLOGICAL MARKERS</subject><subject>Biomarkers</subject><subject>BLOOD</subject><subject>CADMIUM</subject><subject>Chemical and industrial products toxicology. Toxic occupational diseases</subject><subject>CONCENTRATION RATIO</subject><subject>CREATININE</subject><subject>Cross-Sectional Studies</subject><subject>DIET</subject><subject>DRINKING WATER</subject><subject>Dust</subject><subject>DUSTS</subject><subject>ECOLOGICAL CONCENTRATION</subject><subject>Environment</subject><subject>Environmental Exposure - statistics & numerical data</subject><subject>ENVIRONMENTAL MATERIALS</subject><subject>Exposure</subject><subject>Female</subject><subject>FOLIC ACID</subject><subject>HEAVY METALS</subject><subject>Humans</subject><subject>ICP MASS SPECTROSCOPY</subject><subject>IRON</subject><subject>LEAD</subject><subject>Lead (metal)</subject><subject>Linear Models</subject><subject>Maternal</subject><subject>Mathematical models</subject><subject>Medical sciences</subject><subject>MERCURY</subject><subject>Mercury (metal)</subject><subject>Metals and various inorganic compounds</subject><subject>Metals, Heavy - blood</subject><subject>Metals, Heavy - urine</subject><subject>PETROLEUM RESIDUES</subject><subject>PREGNANCY</subject><subject>SMOKES</subject><subject>SOCIO-ECONOMIC FACTORS</subject><subject>SOILS</subject><subject>Toxicology</subject><subject>URINE</subject><subject>WESTERN AUSTRALIA</subject><subject>Young Adult</subject><issn>0013-9351</issn><issn>1096-0953</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqN0V2L1DAUBuAiiju7-g9ECiLsha05zffNogx-wYI3eh0y6emasU3GpF3df2-Gjnqn3iSEPElOzltVT4C0QEC83LcYbhPmtiNAWyJbQvi9agNEi4ZoTu9XG1J2Gk05nFXnOe_LEjglD6uzjipdnN5Ur7a2n_wyvahHtH1tQ19PmNyS7mr8cYh5SVj7UIcY6jzFrz7c1IeEN8GGuf4eJwyPqgeDHTM-Ps0X1ee3bz5t3zfXH9992L6-bhzn3dwAhwHpoJiVA5VSsg5LkYSrHeVU0h0OgvbDQAUKrQF6wWyHQJRU3NkeKL2onq33xjx7k52f0X1xMQR0s-m6jgnNWVGXqzqk-G3BPJvJZ4fjaAPGJRsQQisFIOn_UAa6U6D_TRljVEP5TaFspS7FnBMO5pD8ZNOdAWKOuZm9WXMzx9wMkabkVo49Pb2w7Cbsfx_6FVQBz0_AZmfHIdngfP7jpBKqDMVdrQ5LFrce07FVGBz2Ph071Uf_90p-Ag2GtNs</recordid><startdate>20131001</startdate><enddate>20131001</enddate><creator>Hinwood, A.L.</creator><creator>Callan, A.C.</creator><creator>Ramalingam, M.</creator><creator>Boyce, M.</creator><creator>Heyworth, J.</creator><creator>McCafferty, P.</creator><creator>Odland, J.Ø.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7ST</scope><scope>C1K</scope><scope>SOI</scope><scope>8FD</scope><scope>FR3</scope><scope>KR7</scope><scope>OTOTI</scope></search><sort><creationdate>20131001</creationdate><title>Cadmium, lead and mercury exposure in non smoking pregnant women</title><author>Hinwood, A.L. ; Callan, A.C. ; Ramalingam, M. ; Boyce, M. ; Heyworth, J. ; McCafferty, P. ; Odland, J.Ø.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c552t-151fe3f84a7f377742e095058b35373bef63dff36e69911d64a2e108785cad133</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>60 APPLIED LIFE SCIENCES</topic><topic>ABUNDANCE</topic><topic>Adult</topic><topic>Biological</topic><topic>Biological and medical sciences</topic><topic>BIOLOGICAL MARKERS</topic><topic>Biomarkers</topic><topic>BLOOD</topic><topic>CADMIUM</topic><topic>Chemical and industrial products toxicology. Toxic occupational diseases</topic><topic>CONCENTRATION RATIO</topic><topic>CREATININE</topic><topic>Cross-Sectional Studies</topic><topic>DIET</topic><topic>DRINKING WATER</topic><topic>Dust</topic><topic>DUSTS</topic><topic>ECOLOGICAL CONCENTRATION</topic><topic>Environment</topic><topic>Environmental Exposure - statistics & numerical data</topic><topic>ENVIRONMENTAL MATERIALS</topic><topic>Exposure</topic><topic>Female</topic><topic>FOLIC ACID</topic><topic>HEAVY METALS</topic><topic>Humans</topic><topic>ICP MASS SPECTROSCOPY</topic><topic>IRON</topic><topic>LEAD</topic><topic>Lead (metal)</topic><topic>Linear Models</topic><topic>Maternal</topic><topic>Mathematical models</topic><topic>Medical sciences</topic><topic>MERCURY</topic><topic>Mercury (metal)</topic><topic>Metals and various inorganic compounds</topic><topic>Metals, Heavy - blood</topic><topic>Metals, Heavy - urine</topic><topic>PETROLEUM RESIDUES</topic><topic>PREGNANCY</topic><topic>SMOKES</topic><topic>SOCIO-ECONOMIC FACTORS</topic><topic>SOILS</topic><topic>Toxicology</topic><topic>URINE</topic><topic>WESTERN AUSTRALIA</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hinwood, A.L.</creatorcontrib><creatorcontrib>Callan, A.C.</creatorcontrib><creatorcontrib>Ramalingam, M.</creatorcontrib><creatorcontrib>Boyce, M.</creatorcontrib><creatorcontrib>Heyworth, J.</creatorcontrib><creatorcontrib>McCafferty, P.</creatorcontrib><creatorcontrib>Odland, J.Ø.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Environment Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Civil Engineering Abstracts</collection><collection>OSTI.GOV</collection><jtitle>Environmental research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hinwood, A.L.</au><au>Callan, A.C.</au><au>Ramalingam, M.</au><au>Boyce, M.</au><au>Heyworth, J.</au><au>McCafferty, P.</au><au>Odland, J.Ø.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cadmium, lead and mercury exposure in non smoking pregnant women</atitle><jtitle>Environmental research</jtitle><addtitle>Environ Res</addtitle><date>2013-10-01</date><risdate>2013</risdate><volume>126</volume><spage>118</spage><epage>124</epage><pages>118-124</pages><issn>0013-9351</issn><eissn>1096-0953</eissn><coden>ENVRAL</coden><abstract><![CDATA[Recent literature suggests that exposure to low concentrations of heavy metals may affect both maternal and child health. This study aimed to determine the biological heavy metals concentrations of pregnant women as well as environmental and dietary factors that may influence exposure concentrations. One hundred and seventy three pregnant women were recruited from Western Australia, each providing a sample of blood, first morning void urine, residential soil, dust and drinking water samples. Participants also completed a questionnaire which included a food frequency component. All biological and environmental samples were analysed for heavy metals using ICP-MS. Biological and environmental concentrations of lead and mercury were generally low (Median Pb Drinking Water (DW) 0.04µg/L; Pb soil <3.0µg/g; Pb dust 16.5µg/g; Pb blood 3.67µg/L; Pb urine 0.55; µg/L Hg DW <0.03; Hg soil <1.0µg/g; Hg dust <1.0µg/g; Hg blood 0.46µg/L; Hg urine <0.40µg/L). Cadmium concentrations were low in environmental samples (Median CdDW 0.02µg/L; Cdsoil <0.30ug/g; Cddust <0.30) but elevated in urine samples (Median 0.55µg/L, creatinine corrected 0.70µg/g (range <0.2–7.06µg/g creatinine) compared with other studies of pregnant women. Predictors of increased biological metals concentrations in regression models for blood cadmium were residing in the Great Southern region of Western Australia and not using iron/folic acid supplements and for urinary cadmium was having lower household annual income. However, these factors explained little of the variation in respective biological metals concentrations. The importance of establishing factors that influence low human exposure concentrations is becoming critical in efforts to reduce exposures and hence the potential for adverse health effects.
•Biological heavy metals concentrations in women in their 3rd trimester of pregnancy.•Exposure assessment including environmental, lifestyle and activity data.•Urinary cadmium concentrations were elevated in this group of pregnant women.•Blood lead and mercury concentrations were below recommended biological guideline values.]]></abstract><cop>Amsterdam</cop><pub>Elsevier Inc</pub><pmid>23890969</pmid><doi>10.1016/j.envres.2013.07.005</doi><tpages>7</tpages></addata></record> |
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| subjects | 60 APPLIED LIFE SCIENCES ABUNDANCE Adult Biological Biological and medical sciences BIOLOGICAL MARKERS Biomarkers BLOOD CADMIUM Chemical and industrial products toxicology. Toxic occupational diseases CONCENTRATION RATIO CREATININE Cross-Sectional Studies DIET DRINKING WATER Dust DUSTS ECOLOGICAL CONCENTRATION Environment Environmental Exposure - statistics & numerical data ENVIRONMENTAL MATERIALS Exposure Female FOLIC ACID HEAVY METALS Humans ICP MASS SPECTROSCOPY IRON LEAD Lead (metal) Linear Models Maternal Mathematical models Medical sciences MERCURY Mercury (metal) Metals and various inorganic compounds Metals, Heavy - blood Metals, Heavy - urine PETROLEUM RESIDUES PREGNANCY SMOKES SOCIO-ECONOMIC FACTORS SOILS Toxicology URINE WESTERN AUSTRALIA Young Adult |
| title | Cadmium, lead and mercury exposure in non smoking pregnant women |
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