Enrichment and terminal differentiation of striated muscle progenitors in vitro

Enrichment and terminal differentiation of mammalian striated muscle cells is severely hampered by fibroblast overgrowth, de-differentiation and/or lack of functional differentiation. Herein we report a new, reproducible and simple method to enrich and terminally differentiate muscle stem cells and...

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Veröffentlicht in:	Experimental cell research 2009-10, Vol.315 (16), p.2741-2751
Hauptverfasser:	Becher, Ulrich M., Breitbach, Martin, Sasse, Philipp, Garbe, Stephan, van der Ven, Peter F.M., Fürst, Dieter O., Fleischmann, Bernd K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals BIOLOGICAL RADIATION EFFECTS Cell culture Cell Culture Techniques Cell Differentiation - drug effects Cell Differentiation - physiology Cell Differentiation - radiation effects Cells, Cultured Cellular biology FIBROBLASTS GAMMA RADIATION Gamma Rays Humans IN VITRO IRRADIATION Male MICE MITOMYCIN Mitomycin - pharmacology Muscle satellite cells Muscle, Striated - cytology Muscle, Striated - drug effects Muscle, Striated - physiology Muscle, Striated - radiation effects MUSCLES Muscular system Myocytes, Cardiac - cytology Myocytes, Cardiac - metabolism Nucleic Acid Synthesis Inhibitors - pharmacology Proliferation RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS Scientific method STEM CELLS Stem Cells - cytology Stem Cells - drug effects Stem Cells - physiology Stem Cells - radiation effects Terminal differentiation
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