Chronic exercise ameliorates the neuroinflammation in mice carrying NSE/htau23

► The progress of neurodegeration are directly linked to the neuroinflammatory response. ► We investigate whether exercise improves the neuroinflammation using T g- NSE/htau23 mice. ► This provides insights that exercise may beneficial effects on the neuroinflammatory disorders. The objective of the...

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Veröffentlicht in:	Biochemical and biophysical research communications 2011-03, Vol.406 (3), p.359-365
Hauptverfasser:	Leem, Yea-Hyun, Lee, Young-Ik, Son, Hee-Jeong, Lee, Sang-Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES AGE DEPENDENCE Alzheimer Disease - metabolism Alzheimer Disease - pathology Alzheimer Disease - therapy Animals Astrocytes - metabolism Astrocytes - pathology BRAIN Brain - metabolism Brain - pathology Chronic exercise Cytokines - antagonists & inhibitors Cytokines - metabolism Encephalitis - metabolism Encephalitis - pathology Encephalitis - therapy Gliosis Humans MAXIMUM ACCEPTABLE CONTAMINATION MICE Mice, Transgenic Microglia - metabolism Microglia - pathology MORPHOLOGICAL CHANGES NERVOUS SYSTEM DISEASES Neurofibrillary tangles Neuroinflammation NEUTRON SPECTROSCOPY NSE/htau23 PATHOLOGY Phosphopyruvate Hydratase - genetics Physical Conditioning, Animal Promoter Regions, Genetic SPIN ECHO tau Proteins - genetics tau Proteins - metabolism
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