Vimentin binds IRAP and is involved in GLUT4 vesicle trafficking

► Vimentin is shown to bind to the N-terminus of insulin-responsive aminopeptidase (IRAP), a major cargo protein of GLUT4 vesicles in 3T3-L1 adipocytes. ► GLUT4 translocation to the plasma membrane by insulin is decreased in vimentin-depleted adipocytes. ► An interaction between vimentin and IRAP fu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 2011-02, Vol.405 (1), p.96-101
Hauptverfasser:	Hirata, Yohko, Hosaka, Toshio, Iwata, Takeo, Le, Chung T.K., Jambaldorj, Bayasgalan, Teshigawara, Kiyoshi, Harada, Nagakatsu, Sakaue, Hiroshi, Sakai, Tohru, Yoshimoto, Katsuhiko, Nakaya, Yutaka
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3-L1 Cells 60 APPLIED LIFE SCIENCES Animals Cystinyl Aminopeptidase - metabolism Cytoplasmic Vesicles - metabolism Gene Knockdown Techniques Glucose Transporter Type 4 - metabolism GLUT4 IMMUNOASSAY INSULIN IRAP MEMBRANES Mice MICROTUBULES Protein Transport TRANSLOCATION Vimentin Vimentin - genetics Vimentin - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!