Calcium-sensing receptor activation contributed to apoptosis stimulates TRPC6 channel in rat neonatal ventricular myocytes

Capacitative calcium entry (CCE) refers to the influx of calcium through plasma membrane channels activated on depletion of endoplasmic sarcoplasmic/reticulum (ER/SR) Ca 2+ stores, which is performed mainly by the transient receptor potential (TRP) channels. TRP channels are expressed in cardiomyocy...

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Veröffentlicht in:	Biochemical and biophysical research communications 2010-04, Vol.394 (4), p.955-961
Hauptverfasser:	Sun, Yi-hua, Li, Yong-quan, Feng, Shan-li, Li, Bao-xin, Pan, Zhen-wei, Xu, Chang-qing, Li, Ting-ting, Yang, Bao-feng
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES ANIMAL TISSUES Animals APOPTOSIS CALCIUM Calcium - metabolism Calcium Channel Blockers - pharmacology CALCIUM IONS Calcium-sensing receptor Cardiomyocyte CONCENTRATION RATIO Gadolinium - pharmacology HEART Heart Ventricles - cytology Heart Ventricles - metabolism Imidazoles - pharmacology Muscle Cells - metabolism RATS Rats, Wistar RECEPTORS Receptors, Calcium-Sensing - agonists SARCOPLASMIC RETICULUM SODIUM IONS Thapsigargin - pharmacology Transient receptor potential channels TRPC Cation Channels - agonists
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