Assessing cytotoxicity of boron nitride nanotubes: Interference with the MTT assay

Thanks to a non-covalent wrapping with glycol-chitosan, highly biocompatible and highly concentrated dispersions of boron nitride nanotubes were obtained and tested on human neuroblastoma cells. A systematic investigation of the cytotoxicity of these nanovectors with several complementary qualitativ...

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Veröffentlicht in:	Biochemical and biophysical research communications 2010-04, Vol.394 (2), p.405-411
Hauptverfasser:	Ciofani, Gianni, Danti, Serena, D’Alessandro, Delfo, Moscato, Stefania, Menciassi, Arianna
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES AMINO ACIDS Boron Compounds - chemistry Boron Compounds - toxicity Boron nitride nanotubes BORON NITRIDES CARBON NANOTUBES Cell Line, Tumor Cell Proliferation - drug effects Cell Survival - drug effects Chitosan - chemistry Cytocompatibility testing GLYCOLS Humans MTT assay Nanotubes - chemistry Nanotubes - toxicity Neuroblastoma OLIGOSACCHARIDES Tetrazolium Salts - chemistry Tetrazolium Salts - pharmacology Thiazoles - chemistry Thiazoles - pharmacology TOXICITY Toxicity Tests WST-1 assay
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