Generation of human induced pluripotent stem cells from a Bombay individual: Moving towards “universal-donor” red blood cells

Bombay phenotype is one of the rare phenotypes in the ABO blood group system that fails to express ABH antigens on red blood cells. Nonsense or missense mutations in fucosyltransfrase1 (FUT1) and fucosyltransfrase2 (FUT2) genes are known to create this phenotype. This blood group is compatible with...

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Veröffentlicht in:	Biochemical and biophysical research communications 2010-01, Vol.391 (1), p.329-334
Hauptverfasser:	Seifinejad, Ali, Taei, Adeleh, Totonchi, Mehdi, Vazirinasab, Hamed, Hassani, Seideh Nafiseh, Aghdami, Nasser, Shahbazi, Ebrahim, Yazdi, Reza Salman, Salekdeh, Ghasem Hosseini, Baharvand, Hossein
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES ABO Blood-Group System Amino Acid Sequence ANTIGENS Base Sequence BLOOD CELLS Blood Donors Blood group systems BLOOD GROUPS Bombay phenotype Cell Line DNA Erythrocytes - cytology FIBROBLASTS Fibroblasts - cytology Fibroblasts - metabolism Fucosyltransferases - genetics FUT1 and FUT2 genes Galactoside 2-alpha-L-fucosyltransferase Gene Expression GENES GLOBULINS Hematopoiesis Humans IN VITRO Induced pluripotent stem cells KARYOTYPE Kruppel-Like Factor 4 METHYLATION Mutation, Missense MUTATIONS PHENOTYPE Pluripotent Stem Cells - cytology Pluripotent Stem Cells - metabolism STEM CELLS THERAPY TRANSCRIPTION FACTORS Transcription Factors - genetics
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