Single-strand DNA translation initiation step analyzed by Isothermal Titration Calorimetry

Is single-strand DNA translatable? Since the 60s, the question still remains whether or not DNA could be directly translated into protein. Some discrepancies in the results were reported about functional translation of single-strand DNA but all results converged on a similar behavior of RNA and ssDN...

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Veröffentlicht in:	Biochemical and biophysical research communications 2009-07, Vol.385 (3), p.296-301
Hauptverfasser:	Damian, Luminita, Marty-Detraves, Claire, Winterhalter, Mathias, Fournier, Didier, Paquereau, Laurent
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Anti-Bacterial Agents Anti-Bacterial Agents - pharmacology ANTIBIOTICS Aurintricarboxylic Acid Aurintricarboxylic Acid - pharmacology Biochemistry, Molecular Biology CALORIMETRY Calorimetry - methods DNA DNA translation DNA, Single-Stranded DNA, Single-Stranded - metabolism ELONGATION ESCHERICHIA COLI Isothermal Titration Calorimetry Life Sciences Peptide Chain Elongation, Translational Peptide Chain Initiation, Translational Peptide Chain Initiation, Translational - drug effects PROTEINS Ribosomes Ribosomes - metabolism RNA RNA, Messenger RNA, Messenger - metabolism SPECIFICITY TITRATION
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