Induction of IL-6 and inhibition of IL-8 secretion in the human airway cell line Calu-3 by urban particulate matter collected with a modified method of PM sampling

Exposure to particulate matter (PM) induces inflammatory cytokines. In the present study, we evaluated the secretion of IL-6 and IL-8 by an airway cell line exposed to PM with a mean aerodynamic size equal to or less than 10 or 2.5 μm (PM 10 and PM 2.5, respectively) collected in Mexico City, using...

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Veröffentlicht in:	Environmental research 2009-07, Vol.109 (5), p.528-535
Hauptverfasser:	Alfaro-Moreno, Ernesto, Torres, Victor, Miranda, Javier, Martínez, Leticia, García-Cuellar, Claudia, Nawrot, Tim S., Vanaudenaerde, Bart, Hoet, Peter, Ramírez-López, Pavel, Rosas, Irma, Nemery, Benoit, Osornio-Vargas, Alvaro Román
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Air Air Pollutants - toxicity Airway epithelial cells Biological and medical sciences Cell Line CELLULOSE Environmental pollutants toxicology ENZYME IMMUNOASSAY Humans IL-6 IL-8 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY Interleukin-6 - biosynthesis Interleukin-8 - antagonists & inhibitors Interleukin-8 - secretion LYMPHOKINES Medical sciences Microscopy, Electron, Scanning NITRATES Particle Size PIXE ANALYSIS PM 10 PM 2.5 SAMPLING SCANNING ELECTRON MICROSCOPY SECRETION SILICA Toxicology Trachea - drug effects Trachea - metabolism Trachea - secretion X-RAY SPECTROSCOPY
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