Application of synchrotron radiation computed microtomography for quantification of bone microstructure in human and rat bones
This work aims to evaluate histomorphometric quantification by synchrotron radiation computed microto-mography in bones of human and rat specimens. Bones specimens are classified as normal and pathological (for human samples) and irradiated and non-irradiated samples (for rat ones). Human bones are...
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creator | Parreiras Nogueira, Liebert Barroso, Regina Cely Pereira de Almeida, Andre Braz, Delson Almeida, Carlos Eduardo de Borba de Andrade, Cherley Tromba, Giuliana Physics Institute / State University of Rio de Janeiro, 20550-900, Rio de Janeiro Nuclear Instrumentation Laboratory / COPPE / UFRJ, P.O. Box 68509, 21945-970, Rio de Janeiro Laboratory of Radiological Sciences / State University of Rio de Janeiro, Rio de Janeiro Sincrotrone Trieste SCpA, Strada Statale S.S. 14 km 163.5, 34012 Basovizza, Trieste |
description | This work aims to evaluate histomorphometric quantification by synchrotron radiation computed microto-mography in bones of human and rat specimens. Bones specimens are classified as normal and pathological (for human samples) and irradiated and non-irradiated samples (for rat ones). Human bones are specimens which were affected by some injury, or not. Rat bones are specimens which were irradiated, simulating radiotherapy procedures, or not. Images were obtained on SYRMEP beamline at the Elettra Synchrotron Laboratory in Trieste, Italy. The system generated 14 {mu}m tomographic images. The quantification of bone structures were performed directly by the 3D rendered images using a home-made software. Resolution yielded was excellent what facilitate quantification of bone microstructures. |
doi_str_mv | 10.1063/1.3703340 |
format | Conference Proceeding |
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Box 68509, 21945-970, Rio de Janeiro ; Laboratory of Radiological Sciences / State University of Rio de Janeiro, Rio de Janeiro ; Sincrotrone Trieste SCpA, Strada Statale S.S. 14 km 163.5, 34012 Basovizza, Trieste</creator><creatorcontrib>Parreiras Nogueira, Liebert ; Barroso, Regina Cely ; Pereira de Almeida, Andre ; Braz, Delson ; Almeida, Carlos Eduardo de ; Borba de Andrade, Cherley ; Tromba, Giuliana ; Physics Institute / State University of Rio de Janeiro, 20550-900, Rio de Janeiro ; Nuclear Instrumentation Laboratory / COPPE / UFRJ, P.O. Box 68509, 21945-970, Rio de Janeiro ; Laboratory of Radiological Sciences / State University of Rio de Janeiro, Rio de Janeiro ; Sincrotrone Trieste SCpA, Strada Statale S.S. 14 km 163.5, 34012 Basovizza, Trieste</creatorcontrib><description>This work aims to evaluate histomorphometric quantification by synchrotron radiation computed microto-mography in bones of human and rat specimens. Bones specimens are classified as normal and pathological (for human samples) and irradiated and non-irradiated samples (for rat ones). Human bones are specimens which were affected by some injury, or not. Rat bones are specimens which were irradiated, simulating radiotherapy procedures, or not. Images were obtained on SYRMEP beamline at the Elettra Synchrotron Laboratory in Trieste, Italy. The system generated 14 {mu}m tomographic images. The quantification of bone structures were performed directly by the 3D rendered images using a home-made software. Resolution yielded was excellent what facilitate quantification of bone microstructures.</description><identifier>ISSN: 0094-243X</identifier><identifier>EISSN: 1551-7616</identifier><identifier>DOI: 10.1063/1.3703340</identifier><language>eng</language><publisher>United States</publisher><subject>60 APPLIED LIFE SCIENCES ; COMPUTER CODES ; COMPUTER GRAPHICS ; COMPUTERIZED TOMOGRAPHY ; HUMAN POPULATIONS ; IMAGE PROCESSING ; INJURIES ; MICROSTRUCTURE ; RADIOLOGY AND NUCLEAR MEDICINE ; RADIOTHERAPY ; RATS ; RESOLUTION ; SKELETON ; SYNCHROTRON RADIATION</subject><ispartof>AIP conference proceedings, 2012, Vol.1437 (1)</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttps://www.osti.gov/biblio/22004044$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Parreiras Nogueira, Liebert</creatorcontrib><creatorcontrib>Barroso, Regina Cely</creatorcontrib><creatorcontrib>Pereira de Almeida, Andre</creatorcontrib><creatorcontrib>Braz, Delson</creatorcontrib><creatorcontrib>Almeida, Carlos Eduardo de</creatorcontrib><creatorcontrib>Borba de Andrade, Cherley</creatorcontrib><creatorcontrib>Tromba, Giuliana</creatorcontrib><creatorcontrib>Physics Institute / State University of Rio de Janeiro, 20550-900, Rio de Janeiro</creatorcontrib><creatorcontrib>Nuclear Instrumentation Laboratory / COPPE / UFRJ, P.O. Box 68509, 21945-970, Rio de Janeiro</creatorcontrib><creatorcontrib>Laboratory of Radiological Sciences / State University of Rio de Janeiro, Rio de Janeiro</creatorcontrib><creatorcontrib>Sincrotrone Trieste SCpA, Strada Statale S.S. 14 km 163.5, 34012 Basovizza, Trieste</creatorcontrib><title>Application of synchrotron radiation computed microtomography for quantification of bone microstructure in human and rat bones</title><title>AIP conference proceedings</title><description>This work aims to evaluate histomorphometric quantification by synchrotron radiation computed microto-mography in bones of human and rat specimens. Bones specimens are classified as normal and pathological (for human samples) and irradiated and non-irradiated samples (for rat ones). Human bones are specimens which were affected by some injury, or not. Rat bones are specimens which were irradiated, simulating radiotherapy procedures, or not. Images were obtained on SYRMEP beamline at the Elettra Synchrotron Laboratory in Trieste, Italy. The system generated 14 {mu}m tomographic images. The quantification of bone structures were performed directly by the 3D rendered images using a home-made software. Resolution yielded was excellent what facilitate quantification of bone microstructures.</description><subject>60 APPLIED LIFE SCIENCES</subject><subject>COMPUTER CODES</subject><subject>COMPUTER GRAPHICS</subject><subject>COMPUTERIZED TOMOGRAPHY</subject><subject>HUMAN POPULATIONS</subject><subject>IMAGE PROCESSING</subject><subject>INJURIES</subject><subject>MICROSTRUCTURE</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>RADIOTHERAPY</subject><subject>RATS</subject><subject>RESOLUTION</subject><subject>SKELETON</subject><subject>SYNCHROTRON RADIATION</subject><issn>0094-243X</issn><issn>1551-7616</issn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2012</creationdate><recordtype>conference_proceeding</recordtype><recordid>eNpNjktLAzEYRYMoWKsL_0HA9dQvz5lZlqJWKLhRcFcyeTiRTjImmUU3_nYH68LV5XIPh4vQLYEVAcnuyYrVwBiHM7QgQpCqlkSeowVAyyvK2fslusr5E4C2dd0s0Pd6HA9eq-JjwNHhfAy6T7GkuSZl_GnQcRinYg0evJ7HOMSPpMb-iF1M-GtSoXj3T9LFYE9oLmnSZUoW-4D7aVABq2Bmc_mF8jW6cOqQ7c1fLtHb48PrZlvtXp6eN-tdFUnDSmVM2ymn284KDtBR2pJGUSoN5aYhTrSyBQauIaCtFBIct8QRwayhVgur2RLdnbzzI7_P2herex1DsLrsKQXgwDn7AfweYto</recordid><startdate>20120101</startdate><enddate>20120101</enddate><creator>Parreiras Nogueira, Liebert</creator><creator>Barroso, Regina Cely</creator><creator>Pereira de Almeida, Andre</creator><creator>Braz, Delson</creator><creator>Almeida, Carlos Eduardo de</creator><creator>Borba de Andrade, Cherley</creator><creator>Tromba, Giuliana</creator><creator>Physics Institute / State University of Rio de Janeiro, 20550-900, Rio de Janeiro</creator><creator>Nuclear Instrumentation Laboratory / COPPE / UFRJ, P.O. 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Box 68509, 21945-970, Rio de Janeiro ; Laboratory of Radiological Sciences / State University of Rio de Janeiro, Rio de Janeiro ; Sincrotrone Trieste SCpA, Strada Statale S.S. 14 km 163.5, 34012 Basovizza, Trieste</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-o183t-dd9bafc9be5400b22918a226d24d81f5969030f810ce6560f4e1f153ed2ec5ec3</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2012</creationdate><topic>60 APPLIED LIFE SCIENCES</topic><topic>COMPUTER CODES</topic><topic>COMPUTER GRAPHICS</topic><topic>COMPUTERIZED TOMOGRAPHY</topic><topic>HUMAN POPULATIONS</topic><topic>IMAGE PROCESSING</topic><topic>INJURIES</topic><topic>MICROSTRUCTURE</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>RADIOTHERAPY</topic><topic>RATS</topic><topic>RESOLUTION</topic><topic>SKELETON</topic><topic>SYNCHROTRON RADIATION</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Parreiras Nogueira, Liebert</creatorcontrib><creatorcontrib>Barroso, Regina Cely</creatorcontrib><creatorcontrib>Pereira de Almeida, Andre</creatorcontrib><creatorcontrib>Braz, Delson</creatorcontrib><creatorcontrib>Almeida, Carlos Eduardo de</creatorcontrib><creatorcontrib>Borba de Andrade, Cherley</creatorcontrib><creatorcontrib>Tromba, Giuliana</creatorcontrib><creatorcontrib>Physics Institute / State University of Rio de Janeiro, 20550-900, Rio de Janeiro</creatorcontrib><creatorcontrib>Nuclear Instrumentation Laboratory / COPPE / UFRJ, P.O. 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Box 68509, 21945-970, Rio de Janeiro</au><au>Laboratory of Radiological Sciences / State University of Rio de Janeiro, Rio de Janeiro</au><au>Sincrotrone Trieste SCpA, Strada Statale S.S. 14 km 163.5, 34012 Basovizza, Trieste</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Application of synchrotron radiation computed microtomography for quantification of bone microstructure in human and rat bones</atitle><btitle>AIP conference proceedings</btitle><date>2012-01-01</date><risdate>2012</risdate><volume>1437</volume><issue>1</issue><issn>0094-243X</issn><eissn>1551-7616</eissn><abstract>This work aims to evaluate histomorphometric quantification by synchrotron radiation computed microto-mography in bones of human and rat specimens. Bones specimens are classified as normal and pathological (for human samples) and irradiated and non-irradiated samples (for rat ones). Human bones are specimens which were affected by some injury, or not. Rat bones are specimens which were irradiated, simulating radiotherapy procedures, or not. Images were obtained on SYRMEP beamline at the Elettra Synchrotron Laboratory in Trieste, Italy. The system generated 14 {mu}m tomographic images. The quantification of bone structures were performed directly by the 3D rendered images using a home-made software. Resolution yielded was excellent what facilitate quantification of bone microstructures.</abstract><cop>United States</cop><doi>10.1063/1.3703340</doi></addata></record> |
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subjects | 60 APPLIED LIFE SCIENCES COMPUTER CODES COMPUTER GRAPHICS COMPUTERIZED TOMOGRAPHY HUMAN POPULATIONS IMAGE PROCESSING INJURIES MICROSTRUCTURE RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY RATS RESOLUTION SKELETON SYNCHROTRON RADIATION |
title | Application of synchrotron radiation computed microtomography for quantification of bone microstructure in human and rat bones |
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