Application of synchrotron radiation computed microtomography for quantification of bone microstructure in human and rat bones

This work aims to evaluate histomorphometric quantification by synchrotron radiation computed microto-mography in bones of human and rat specimens. Bones specimens are classified as normal and pathological (for human samples) and irradiated and non-irradiated samples (for rat ones). Human bones are...

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Hauptverfasser: Parreiras Nogueira, Liebert, Barroso, Regina Cely, Pereira de Almeida, Andre, Braz, Delson, Almeida, Carlos Eduardo de, Borba de Andrade, Cherley, Tromba, Giuliana, Physics Institute / State University of Rio de Janeiro, 20550-900, Rio de Janeiro, Nuclear Instrumentation Laboratory / COPPE / UFRJ, P.O. Box 68509, 21945-970, Rio de Janeiro, Laboratory of Radiological Sciences / State University of Rio de Janeiro, Rio de Janeiro, Sincrotrone Trieste SCpA, Strada Statale S.S. 14 km 163.5, 34012 Basovizza, Trieste
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creator Parreiras Nogueira, Liebert
Barroso, Regina Cely
Pereira de Almeida, Andre
Braz, Delson
Almeida, Carlos Eduardo de
Borba de Andrade, Cherley
Tromba, Giuliana
Physics Institute / State University of Rio de Janeiro, 20550-900, Rio de Janeiro
Nuclear Instrumentation Laboratory / COPPE / UFRJ, P.O. Box 68509, 21945-970, Rio de Janeiro
Laboratory of Radiological Sciences / State University of Rio de Janeiro, Rio de Janeiro
Sincrotrone Trieste SCpA, Strada Statale S.S. 14 km 163.5, 34012 Basovizza, Trieste
description This work aims to evaluate histomorphometric quantification by synchrotron radiation computed microto-mography in bones of human and rat specimens. Bones specimens are classified as normal and pathological (for human samples) and irradiated and non-irradiated samples (for rat ones). Human bones are specimens which were affected by some injury, or not. Rat bones are specimens which were irradiated, simulating radiotherapy procedures, or not. Images were obtained on SYRMEP beamline at the Elettra Synchrotron Laboratory in Trieste, Italy. The system generated 14 {mu}m tomographic images. The quantification of bone structures were performed directly by the 3D rendered images using a home-made software. Resolution yielded was excellent what facilitate quantification of bone microstructures.
doi_str_mv 10.1063/1.3703340
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subjects 60 APPLIED LIFE SCIENCES
COMPUTER CODES
COMPUTER GRAPHICS
COMPUTERIZED TOMOGRAPHY
HUMAN POPULATIONS
IMAGE PROCESSING
INJURIES
MICROSTRUCTURE
RADIOLOGY AND NUCLEAR MEDICINE
RADIOTHERAPY
RATS
RESOLUTION
SKELETON
SYNCHROTRON RADIATION
title Application of synchrotron radiation computed microtomography for quantification of bone microstructure in human and rat bones
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