Sulfation of chlorotyrosine and nitrotyrosine by human lung endothelial and epithelial cells: Role of the human SULT1A3

During inflammation, potent reactive oxidants formed may cause chlorination and nitration of both free and protein-bound tyrosine. In addition to serving as biomarkers of inflammation-mediated oxidative stress, elevated levels of chlorotyrosine and nitrotyrosine have been linked to the pathogenesis...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Toxicology and applied pharmacology 2011-03, Vol.251 (2), p.104-109
Hauptverfasser:	Yasuda, Shin, Yasuda, Tomoko, Liu, Ming-Yih, Shetty, Sreerama, Idell, Steven, Boggaram, Vijayakumar, Suiko, Masahito, Sakakibara, Yoichi, Fu, Jian, Liu, Ming-Cheh
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES AMINO ACIDS ANIMAL CELLS Arylsulfotransferase Biological and medical sciences BIOLOGICAL MARKERS BODY CARBOXYLIC ACIDS Cell Line CHEMICAL REACTIONS CHLORINATION Chlorotyrosine Endothelial Cells - metabolism Endothelial Cells - pathology ENZYMES GENE AMPLIFICATION HALOGENATION HUMAN POPULATIONS Humans HYDROXY ACIDS INFLAMMATION Inflammation Mediators - physiology LABELLING Lung - metabolism Lung - pathology LUNGS Medical sciences NITRATION Nitrotyrosine ORGANIC ACIDS ORGANIC COMPOUNDS ORGANS OXIDATION OXYGEN COMPOUNDS PATHOGENESIS PATHOLOGICAL CHANGES POLYMERASE CHAIN REACTION POPULATIONS PROTEINS Respiratory Mucosa - metabolism Respiratory Mucosa - pathology RESPIRATORY SYSTEM RESPIRATORY TRACT CELLS SOMATIC CELLS SULFATES Sulfates - chemistry Sulfates - metabolism SULFATION Sulfotransferase Sulfotransferases - physiology SULFUR COMPOUNDS SULT1A3 SYMPTOMS Toxicology TYROSINE Tyrosine - analogs & derivatives Tyrosine - antagonists & inhibitors Tyrosine - chemistry Tyrosine - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!