Real-Time Target Position Estimation Using Stereoscopic Kilovoltage/Megavoltage Imaging and External Respiratory Monitoring for Dynamic Multileaf Collimator Tracking
Purpose To develop a real-time target position estimation method using stereoscopic kilovoltage (kV)/megavoltage (MV) imaging and external respiratory monitoring, and to investigate the performance of a dynamic multileaf collimator tracking system using this method. Methods and Materials The real-ti...
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| Veröffentlicht in: | International journal of radiation oncology, biology, physics biology, physics, 2011, Vol.79 (1), p.269-278 |
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| creator | Cho, Byungchul, Ph.D Poulsen, Per Rugaard, Ph.D Sawant, Amit, Ph.D Ruan, Dan, Ph.D Keall, Paul J., Ph.D |
| description | Purpose To develop a real-time target position estimation method using stereoscopic kilovoltage (kV)/megavoltage (MV) imaging and external respiratory monitoring, and to investigate the performance of a dynamic multileaf collimator tracking system using this method. Methods and Materials The real-time three-dimensional internal target position estimation was established by creating a time-varying correlation model that connected the external respiratory signals with the internal target motion measured intermittently using kV/MV imaging. The method was integrated into a dynamic multileaf collimator tracking system. Tracking experiments were performed for 10 thoracic/abdominal traces. A three-dimensional motion platform carrying a gold marker and a separate one-dimensional motion platform were used to reproduce the target and external respiratory motion, respectively. The target positions were detected by kV (1 Hz) and MV (5.2 Hz) imaging, and external respiratory motion was captured by an optical system (30 Hz). The beam–target alignment error was quantified as the positional difference between the target and circular beam center on the MV images acquired during tracking. The correlation model error was quantified by comparing a model estimate and measured target positions. Results The root-mean-square errors in the beam–target alignment that had ranged from 3.1 to 7.6 mm without tracking were reduced to |
| doi_str_mv | 10.1016/j.ijrobp.2010.02.052 |
| format | Article |
| fullrecord | <record><control><sourceid>elsevier_osti_</sourceid><recordid>TN_cdi_osti_scitechconnect_21499711</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S036030161000413X</els_id><sourcerecordid>1_s2_0_S036030161000413X</sourcerecordid><originalsourceid>FETCH-LOGICAL-c586t-ef71e48366f668fe20fda0ee6f68b4ff7a5e296f652db10bf38a230cc56227343</originalsourceid><addsrcrecordid>eNqFkttuEzEQhlcIREPhDRCyhLjc1Ic93iChEKCiEahNpd5ZjnccvPXakb2pyAPxnsySABI3XHlsf__M2P9k2UtG54yy6qKf2z6GzW7OKR5RPqclf5TNWFO3uSjLu8fZjIqK5gLhs-xZSj2llLG6eJqdcVqxsuJilv24BuXytR2ArFXcwki-hmRHGzxZptEO6ld4m6zfkpsRIoSkw85q8tm68BDcqLZwsYKtOsXkclDbCVa-I8vvqPDKkWtIOxvVGOKBrIK3GEyMCZG8P3g1YL7V3o3WgTJkEZybCuPlOip9j-Tz7IlRLsGL03qe3X5Yrhef8qsvHy8X765yXTbVmIOpGRSNqCpTVY0BTk2nKABum01hTK1K4C3uSt5tGN0Y0SguqNb4F7wWhTjPXh_zBny7TNqOoL_p4D3oUXJWtG3NGFLFkdIxpBTByF3EhuNBMionb2Qvj97IyRtJuURvUPbqKNvtNwN0f0S_zUDgzQlQSStnovLapr-caEXdiAa5t0cO8CseLMSpU_AaOhunRrtg_9fJvwm0s95izXs4QOrDfnItSSYTCuTNNEfTGDGcoIKJO_ETIr_Hnw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Real-Time Target Position Estimation Using Stereoscopic Kilovoltage/Megavoltage Imaging and External Respiratory Monitoring for Dynamic Multileaf Collimator Tracking</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Cho, Byungchul, Ph.D ; Poulsen, Per Rugaard, Ph.D ; Sawant, Amit, Ph.D ; Ruan, Dan, Ph.D ; Keall, Paul J., Ph.D</creator><creatorcontrib>Cho, Byungchul, Ph.D ; Poulsen, Per Rugaard, Ph.D ; Sawant, Amit, Ph.D ; Ruan, Dan, Ph.D ; Keall, Paul J., Ph.D</creatorcontrib><description>Purpose To develop a real-time target position estimation method using stereoscopic kilovoltage (kV)/megavoltage (MV) imaging and external respiratory monitoring, and to investigate the performance of a dynamic multileaf collimator tracking system using this method. Methods and Materials The real-time three-dimensional internal target position estimation was established by creating a time-varying correlation model that connected the external respiratory signals with the internal target motion measured intermittently using kV/MV imaging. The method was integrated into a dynamic multileaf collimator tracking system. Tracking experiments were performed for 10 thoracic/abdominal traces. A three-dimensional motion platform carrying a gold marker and a separate one-dimensional motion platform were used to reproduce the target and external respiratory motion, respectively. The target positions were detected by kV (1 Hz) and MV (5.2 Hz) imaging, and external respiratory motion was captured by an optical system (30 Hz). The beam–target alignment error was quantified as the positional difference between the target and circular beam center on the MV images acquired during tracking. The correlation model error was quantified by comparing a model estimate and measured target positions. Results The root-mean-square errors in the beam–target alignment that had ranged from 3.1 to 7.6 mm without tracking were reduced to <1.5 mm with tracking, except during the model building period (6 s). The root-mean-square error in the correlation model was submillimeters in all directions. Conclusion A novel real-time target position estimation method was developed and integrated into a dynamic multileaf collimator tracking system and demonstrated an average submillimeter geometric accuracy after initializing the internal/external correlation model. The method used hardware tools available on linear accelerators and therefore shows promise for clinical implementation.</description><identifier>ISSN: 0360-3016</identifier><identifier>EISSN: 1879-355X</identifier><identifier>DOI: 10.1016/j.ijrobp.2010.02.052</identifier><identifier>PMID: 20615623</identifier><identifier>CODEN: IOBPD3</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Abdominal Neoplasms - diagnostic imaging ; Abdominal Neoplasms - radiotherapy ; ACCELERATORS ; ALIGNMENT ; Biological and medical sciences ; Calibration ; Clinical Protocols ; COLLIMATORS ; Computer Systems ; CORRELATIONS ; DISEASES ; dynamic multileaf collimator ; Equipment Design ; ERRORS ; external respiratory surrogate ; Hematology, Oncology and Palliative Medicine ; Humans ; LINEAR ACCELERATORS ; Medical sciences ; MONITORING ; MOTION ; Movement - physiology ; NEOPLASMS ; Particle Accelerators - instrumentation ; POSITIONING ; Radiography ; Radiology ; RADIOLOGY AND NUCLEAR MEDICINE ; REAL TIME SYSTEMS ; Real-time tumor tracking ; RESPIRATION ; respiratory tumor motion ; SIGNALS ; Technology, Radiologic - instrumentation ; Technology, Radiologic - methods ; Thoracic Neoplasms - diagnostic imaging ; Thoracic Neoplasms - radiotherapy ; Time Factors ; Treatment with physical agents ; Treatment. General aspects ; Tumors ; x-ray image guidance</subject><ispartof>International journal of radiation oncology, biology, physics, 2011, Vol.79 (1), p.269-278</ispartof><rights>Elsevier Inc.</rights><rights>2011 Elsevier Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c586t-ef71e48366f668fe20fda0ee6f68b4ff7a5e296f652db10bf38a230cc56227343</citedby><cites>FETCH-LOGICAL-c586t-ef71e48366f668fe20fda0ee6f68b4ff7a5e296f652db10bf38a230cc56227343</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S036030161000413X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,4010,27900,27901,27902,65534</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23937838$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20615623$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/21499711$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Cho, Byungchul, Ph.D</creatorcontrib><creatorcontrib>Poulsen, Per Rugaard, Ph.D</creatorcontrib><creatorcontrib>Sawant, Amit, Ph.D</creatorcontrib><creatorcontrib>Ruan, Dan, Ph.D</creatorcontrib><creatorcontrib>Keall, Paul J., Ph.D</creatorcontrib><title>Real-Time Target Position Estimation Using Stereoscopic Kilovoltage/Megavoltage Imaging and External Respiratory Monitoring for Dynamic Multileaf Collimator Tracking</title><title>International journal of radiation oncology, biology, physics</title><addtitle>Int J Radiat Oncol Biol Phys</addtitle><description>Purpose To develop a real-time target position estimation method using stereoscopic kilovoltage (kV)/megavoltage (MV) imaging and external respiratory monitoring, and to investigate the performance of a dynamic multileaf collimator tracking system using this method. Methods and Materials The real-time three-dimensional internal target position estimation was established by creating a time-varying correlation model that connected the external respiratory signals with the internal target motion measured intermittently using kV/MV imaging. The method was integrated into a dynamic multileaf collimator tracking system. Tracking experiments were performed for 10 thoracic/abdominal traces. A three-dimensional motion platform carrying a gold marker and a separate one-dimensional motion platform were used to reproduce the target and external respiratory motion, respectively. The target positions were detected by kV (1 Hz) and MV (5.2 Hz) imaging, and external respiratory motion was captured by an optical system (30 Hz). The beam–target alignment error was quantified as the positional difference between the target and circular beam center on the MV images acquired during tracking. The correlation model error was quantified by comparing a model estimate and measured target positions. Results The root-mean-square errors in the beam–target alignment that had ranged from 3.1 to 7.6 mm without tracking were reduced to <1.5 mm with tracking, except during the model building period (6 s). The root-mean-square error in the correlation model was submillimeters in all directions. Conclusion A novel real-time target position estimation method was developed and integrated into a dynamic multileaf collimator tracking system and demonstrated an average submillimeter geometric accuracy after initializing the internal/external correlation model. The method used hardware tools available on linear accelerators and therefore shows promise for clinical implementation.</description><subject>Abdominal Neoplasms - diagnostic imaging</subject><subject>Abdominal Neoplasms - radiotherapy</subject><subject>ACCELERATORS</subject><subject>ALIGNMENT</subject><subject>Biological and medical sciences</subject><subject>Calibration</subject><subject>Clinical Protocols</subject><subject>COLLIMATORS</subject><subject>Computer Systems</subject><subject>CORRELATIONS</subject><subject>DISEASES</subject><subject>dynamic multileaf collimator</subject><subject>Equipment Design</subject><subject>ERRORS</subject><subject>external respiratory surrogate</subject><subject>Hematology, Oncology and Palliative Medicine</subject><subject>Humans</subject><subject>LINEAR ACCELERATORS</subject><subject>Medical sciences</subject><subject>MONITORING</subject><subject>MOTION</subject><subject>Movement - physiology</subject><subject>NEOPLASMS</subject><subject>Particle Accelerators - instrumentation</subject><subject>POSITIONING</subject><subject>Radiography</subject><subject>Radiology</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>REAL TIME SYSTEMS</subject><subject>Real-time tumor tracking</subject><subject>RESPIRATION</subject><subject>respiratory tumor motion</subject><subject>SIGNALS</subject><subject>Technology, Radiologic - instrumentation</subject><subject>Technology, Radiologic - methods</subject><subject>Thoracic Neoplasms - diagnostic imaging</subject><subject>Thoracic Neoplasms - radiotherapy</subject><subject>Time Factors</subject><subject>Treatment with physical agents</subject><subject>Treatment. General aspects</subject><subject>Tumors</subject><subject>x-ray image guidance</subject><issn>0360-3016</issn><issn>1879-355X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkttuEzEQhlcIREPhDRCyhLjc1Ic93iChEKCiEahNpd5ZjnccvPXakb2pyAPxnsySABI3XHlsf__M2P9k2UtG54yy6qKf2z6GzW7OKR5RPqclf5TNWFO3uSjLu8fZjIqK5gLhs-xZSj2llLG6eJqdcVqxsuJilv24BuXytR2ArFXcwki-hmRHGzxZptEO6ld4m6zfkpsRIoSkw85q8tm68BDcqLZwsYKtOsXkclDbCVa-I8vvqPDKkWtIOxvVGOKBrIK3GEyMCZG8P3g1YL7V3o3WgTJkEZybCuPlOip9j-Tz7IlRLsGL03qe3X5Yrhef8qsvHy8X765yXTbVmIOpGRSNqCpTVY0BTk2nKABum01hTK1K4C3uSt5tGN0Y0SguqNb4F7wWhTjPXh_zBny7TNqOoL_p4D3oUXJWtG3NGFLFkdIxpBTByF3EhuNBMionb2Qvj97IyRtJuURvUPbqKNvtNwN0f0S_zUDgzQlQSStnovLapr-caEXdiAa5t0cO8CseLMSpU_AaOhunRrtg_9fJvwm0s95izXs4QOrDfnItSSYTCuTNNEfTGDGcoIKJO_ETIr_Hnw</recordid><startdate>2011</startdate><enddate>2011</enddate><creator>Cho, Byungchul, Ph.D</creator><creator>Poulsen, Per Rugaard, Ph.D</creator><creator>Sawant, Amit, Ph.D</creator><creator>Ruan, Dan, Ph.D</creator><creator>Keall, Paul J., Ph.D</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>2011</creationdate><title>Real-Time Target Position Estimation Using Stereoscopic Kilovoltage/Megavoltage Imaging and External Respiratory Monitoring for Dynamic Multileaf Collimator Tracking</title><author>Cho, Byungchul, Ph.D ; Poulsen, Per Rugaard, Ph.D ; Sawant, Amit, Ph.D ; Ruan, Dan, Ph.D ; Keall, Paul J., Ph.D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c586t-ef71e48366f668fe20fda0ee6f68b4ff7a5e296f652db10bf38a230cc56227343</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Abdominal Neoplasms - diagnostic imaging</topic><topic>Abdominal Neoplasms - radiotherapy</topic><topic>ACCELERATORS</topic><topic>ALIGNMENT</topic><topic>Biological and medical sciences</topic><topic>Calibration</topic><topic>Clinical Protocols</topic><topic>COLLIMATORS</topic><topic>Computer Systems</topic><topic>CORRELATIONS</topic><topic>DISEASES</topic><topic>dynamic multileaf collimator</topic><topic>Equipment Design</topic><topic>ERRORS</topic><topic>external respiratory surrogate</topic><topic>Hematology, Oncology and Palliative Medicine</topic><topic>Humans</topic><topic>LINEAR ACCELERATORS</topic><topic>Medical sciences</topic><topic>MONITORING</topic><topic>MOTION</topic><topic>Movement - physiology</topic><topic>NEOPLASMS</topic><topic>Particle Accelerators - instrumentation</topic><topic>POSITIONING</topic><topic>Radiography</topic><topic>Radiology</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>REAL TIME SYSTEMS</topic><topic>Real-time tumor tracking</topic><topic>RESPIRATION</topic><topic>respiratory tumor motion</topic><topic>SIGNALS</topic><topic>Technology, Radiologic - instrumentation</topic><topic>Technology, Radiologic - methods</topic><topic>Thoracic Neoplasms - diagnostic imaging</topic><topic>Thoracic Neoplasms - radiotherapy</topic><topic>Time Factors</topic><topic>Treatment with physical agents</topic><topic>Treatment. General aspects</topic><topic>Tumors</topic><topic>x-ray image guidance</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cho, Byungchul, Ph.D</creatorcontrib><creatorcontrib>Poulsen, Per Rugaard, Ph.D</creatorcontrib><creatorcontrib>Sawant, Amit, Ph.D</creatorcontrib><creatorcontrib>Ruan, Dan, Ph.D</creatorcontrib><creatorcontrib>Keall, Paul J., Ph.D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>International journal of radiation oncology, biology, physics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cho, Byungchul, Ph.D</au><au>Poulsen, Per Rugaard, Ph.D</au><au>Sawant, Amit, Ph.D</au><au>Ruan, Dan, Ph.D</au><au>Keall, Paul J., Ph.D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Real-Time Target Position Estimation Using Stereoscopic Kilovoltage/Megavoltage Imaging and External Respiratory Monitoring for Dynamic Multileaf Collimator Tracking</atitle><jtitle>International journal of radiation oncology, biology, physics</jtitle><addtitle>Int J Radiat Oncol Biol Phys</addtitle><date>2011</date><risdate>2011</risdate><volume>79</volume><issue>1</issue><spage>269</spage><epage>278</epage><pages>269-278</pages><issn>0360-3016</issn><eissn>1879-355X</eissn><coden>IOBPD3</coden><abstract>Purpose To develop a real-time target position estimation method using stereoscopic kilovoltage (kV)/megavoltage (MV) imaging and external respiratory monitoring, and to investigate the performance of a dynamic multileaf collimator tracking system using this method. Methods and Materials The real-time three-dimensional internal target position estimation was established by creating a time-varying correlation model that connected the external respiratory signals with the internal target motion measured intermittently using kV/MV imaging. The method was integrated into a dynamic multileaf collimator tracking system. Tracking experiments were performed for 10 thoracic/abdominal traces. A three-dimensional motion platform carrying a gold marker and a separate one-dimensional motion platform were used to reproduce the target and external respiratory motion, respectively. The target positions were detected by kV (1 Hz) and MV (5.2 Hz) imaging, and external respiratory motion was captured by an optical system (30 Hz). The beam–target alignment error was quantified as the positional difference between the target and circular beam center on the MV images acquired during tracking. The correlation model error was quantified by comparing a model estimate and measured target positions. Results The root-mean-square errors in the beam–target alignment that had ranged from 3.1 to 7.6 mm without tracking were reduced to <1.5 mm with tracking, except during the model building period (6 s). The root-mean-square error in the correlation model was submillimeters in all directions. Conclusion A novel real-time target position estimation method was developed and integrated into a dynamic multileaf collimator tracking system and demonstrated an average submillimeter geometric accuracy after initializing the internal/external correlation model. The method used hardware tools available on linear accelerators and therefore shows promise for clinical implementation.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>20615623</pmid><doi>10.1016/j.ijrobp.2010.02.052</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | International journal of radiation oncology, biology, physics, 2011, Vol.79 (1), p.269-278 |
| issn | 0360-3016 1879-355X |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Abdominal Neoplasms - diagnostic imaging Abdominal Neoplasms - radiotherapy ACCELERATORS ALIGNMENT Biological and medical sciences Calibration Clinical Protocols COLLIMATORS Computer Systems CORRELATIONS DISEASES dynamic multileaf collimator Equipment Design ERRORS external respiratory surrogate Hematology, Oncology and Palliative Medicine Humans LINEAR ACCELERATORS Medical sciences MONITORING MOTION Movement - physiology NEOPLASMS Particle Accelerators - instrumentation POSITIONING Radiography Radiology RADIOLOGY AND NUCLEAR MEDICINE REAL TIME SYSTEMS Real-time tumor tracking RESPIRATION respiratory tumor motion SIGNALS Technology, Radiologic - instrumentation Technology, Radiologic - methods Thoracic Neoplasms - diagnostic imaging Thoracic Neoplasms - radiotherapy Time Factors Treatment with physical agents Treatment. General aspects Tumors x-ray image guidance |
| title | Real-Time Target Position Estimation Using Stereoscopic Kilovoltage/Megavoltage Imaging and External Respiratory Monitoring for Dynamic Multileaf Collimator Tracking |
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