Potential for Differentiation of Pseudoprogression From True Tumor Progression With Dynamic Susceptibility-Weighted Contrast-Enhanced Magnetic Resonance Imaging Using Ferumoxytol vs. Gadoteridol: A Pilot Study

Purpose We evaluated dynamic susceptibility-weighted contrast-enhanced magnetic resonance imaging (DSC-MRI) using gadoteridol in comparison to the iron oxide nanoparticle blood pool agent, ferumoxytol, in patients with glioblastoma multiforme (GBM) who received standard radiochemotherapy (RCT). Meth...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2011-02, Vol.79 (2), p.514-523
Hauptverfasser:	Gahramanov, Seymur, M.D, Raslan, Ahmed M., M.D, Muldoon, Leslie L., Ph.D, Hamilton, Bronwyn E., M.D, Rooney, William D., Ph.D, Varallyay, Csanad G., M.D, Njus, Jeffrey M., Ph.D, Haluska, Marianne, A.N.P, Neuwelt, Edward A., M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Blood Volume Blood-Brain Barrier Brain Neoplasms - blood supply Brain Neoplasms - drug therapy Brain Neoplasms - pathology Brain Neoplasms - radiotherapy COMBINED THERAPY CONTRAST MEDIA Contrast media. Radiopharmaceuticals DIAGNOSTIC TECHNIQUES Disease Progression DISEASES Dynamic susceptibility-weighted contrast-enhanced magnetic resonance imaging Female Ferrosoferric Oxide Gadolinium Glioblastoma - blood supply Glioblastoma - drug therapy Glioblastoma - pathology Glioblastoma - radiotherapy Glioblastoma multiforme GLIOMAS Hematology, Oncology and Palliative Medicine Heterocyclic Compounds Humans Magnetic Resonance Imaging - methods Magnetite Nanoparticles Male Medical sciences MEDICINE Middle Aged NEOPLASMS NERVOUS SYSTEM DISEASES Neurology NMR IMAGING Organometallic Compounds Pharmacology. Drug treatments Pilot Projects Pseudoprogression Radiochemotherapy Radiology RADIOLOGY AND NUCLEAR MEDICINE THERAPY Tumors of the nervous system. Phacomatoses Young Adult
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