Early and Late Retrieval of the ALN Removable Vena Cava Filter: Results from a Multicenter Study
Retrieval of removable inferior vena cava (IVC) filters in selected patients is widely practiced. The purpose of this multicenter study was to evaluate the feasibility and results of percutaneous removal of the ALN removable filter in a large patient cohort. Between November 2003 and June 2006, 123...
Gespeichert in:
| Veröffentlicht in: | Cardiovascular and interventional radiology 2008-09, Vol.31 (5), p.889-896 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 896 |
|---|---|
| container_issue | 5 |
| container_start_page | 889 |
| container_title | Cardiovascular and interventional radiology |
| container_volume | 31 |
| creator | Pellerin, O. Barral, F. G. Lions, C. Novelli, L. Beregi, J. P. Sapoval, M. |
| description | Retrieval of removable inferior vena cava (IVC) filters in selected patients is widely practiced. The purpose of this multicenter study was to evaluate the feasibility and results of percutaneous removal of the ALN removable filter in a large patient cohort. Between November 2003 and June 2006, 123 consecutive patients were referred for percutaneous extraction of the ALN filter at three centers. The ALN filter is a removable filter that can be implanted through a femoral/jugular vein approach and extracted by the jugular vein approach. Filter removal was attempted after an implantation period of 93 ± 15 days (range, 6–722 days) through the right internal jugular vein approach using the dedicated extraction kit after control inferior vena cavography. Following filter removal, vena cavograms were obtained in all patients. Successful extraction was achieved in all but one case. Among these successful retrievals, additional manipulation using a femoral approach was needed when the apex of the filter was close to the IVC wall in two patients. No immediate IVC complications were observed according to the postimplantation cavography. Neither technical nor clinical differences between early and late filter retrieval were noticed. Our data confirm the safety of ALN filter retrieval up to 722 days after implantation. In infrequent cases, additional endovenous filter manipulation is needed to facilitate extraction. |
| doi_str_mv | 10.1007/s00270-008-9357-x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_osti_</sourceid><recordid>TN_cdi_osti_scitechconnect_21450336</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69541538</sourcerecordid><originalsourceid>FETCH-LOGICAL-c497t-dc977a44d0c782f4738e43ddfe0afa03afc18dbf19e8b71dc215b35fb706d6503</originalsourceid><addsrcrecordid>eNp1kVuLFDEQhYMo7uzqD_BFgoLgQ2vl1kn7Ngx7EVoFb_gW00na6aEva5Iedv69GXpwQfApVM5Xp6o4CD0j8IYAyLcRgEooAFRRMSGLuwdoRTijBajyx0O0AiJ5QYQgZ-g8xh0AEYqKx-iMKF4xRckK_bw0oT9gMzpcm-TxZ59C5_emx1OL09bjdf0xfw7T3jS9x9_9aPDG7A2-6vrkw7usxblPEbdhGrDBH3LRWT9mDX9Jszs8QY9a00f_9PReoG9Xl183N0X96fr9Zl0XllcyFc5WUhrOHVipaMslU54z51oPpjXATGuJck1LKq8aSZylRDRMtI2E0pUC2AV6ufhOMXU62i55u7XTOHqbNCU8I6zM1OuF2ppe34ZuMOGgJ9Ppm3Wt592gATgHVoo9yeyrhb0N0-_Zx6SHLlrf92b00xx1WQlOBFMZfPEPuJvmMOZrNaWSyZLJI0QWyIYpxuDbv-MJ6GOaekkzb6D0MU19l3uen4znZvDuvuMUXwboAsQsjb98uJ_8f9c_yRiocQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>227376378</pqid></control><display><type>article</type><title>Early and Late Retrieval of the ALN Removable Vena Cava Filter: Results from a Multicenter Study</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Pellerin, O. ; Barral, F. G. ; Lions, C. ; Novelli, L. ; Beregi, J. P. ; Sapoval, M.</creator><creatorcontrib>Pellerin, O. ; Barral, F. G. ; Lions, C. ; Novelli, L. ; Beregi, J. P. ; Sapoval, M.</creatorcontrib><description>Retrieval of removable inferior vena cava (IVC) filters in selected patients is widely practiced. The purpose of this multicenter study was to evaluate the feasibility and results of percutaneous removal of the ALN removable filter in a large patient cohort. Between November 2003 and June 2006, 123 consecutive patients were referred for percutaneous extraction of the ALN filter at three centers. The ALN filter is a removable filter that can be implanted through a femoral/jugular vein approach and extracted by the jugular vein approach. Filter removal was attempted after an implantation period of 93 ± 15 days (range, 6–722 days) through the right internal jugular vein approach using the dedicated extraction kit after control inferior vena cavography. Following filter removal, vena cavograms were obtained in all patients. Successful extraction was achieved in all but one case. Among these successful retrievals, additional manipulation using a femoral approach was needed when the apex of the filter was close to the IVC wall in two patients. No immediate IVC complications were observed according to the postimplantation cavography. Neither technical nor clinical differences between early and late filter retrieval were noticed. Our data confirm the safety of ALN filter retrieval up to 722 days after implantation. In infrequent cases, additional endovenous filter manipulation is needed to facilitate extraction.</description><identifier>ISSN: 0174-1551</identifier><identifier>EISSN: 1432-086X</identifier><identifier>DOI: 10.1007/s00270-008-9357-x</identifier><identifier>PMID: 18493821</identifier><language>eng</language><publisher>New York: Springer-Verlag</publisher><subject>Aged ; Aged, 80 and over ; BLOOD VESSELS ; BODY ; Cardiology ; CARDIOVASCULAR SYSTEM ; Clinical Investigation ; Device Removal ; Device Removal - methods ; Equipment Design ; Equipment Safety ; EXTRACTION ; Feasibility Studies ; Female ; FILTERS ; Follow-Up Studies ; Humans ; Imaging ; Life Sciences ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Nuclear Medicine ; ORGANS ; Pharmaceutical sciences ; Pharmacology ; Pulmonary Embolism ; Pulmonary Embolism - etiology ; Pulmonary Embolism - prevention & control ; Radiography, Interventional ; Radiology ; RADIOLOGY AND NUCLEAR MEDICINE ; REMOVAL ; Retrospective Studies ; Risk Assessment ; SEPARATION PROCESSES ; Time Factors ; Treatment Outcome ; Ultrasound ; VEINS ; Vena Cava Filters ; Vena Cava, Inferior ; Vena Cava, Inferior - diagnostic imaging ; Vena Cava, Inferior - surgery ; Venous Thrombosis ; Venous Thrombosis - complications ; Venous Thrombosis - diagnostic imaging ; Venous Thrombosis - surgery</subject><ispartof>Cardiovascular and interventional radiology, 2008-09, Vol.31 (5), p.889-896</ispartof><rights>Springer Science+Business Media, LLC 2008</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c497t-dc977a44d0c782f4738e43ddfe0afa03afc18dbf19e8b71dc215b35fb706d6503</citedby><cites>FETCH-LOGICAL-c497t-dc977a44d0c782f4738e43ddfe0afa03afc18dbf19e8b71dc215b35fb706d6503</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00270-008-9357-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00270-008-9357-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,780,784,885,27923,27924,41487,42556,51318</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18493821$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://ujm.hal.science/ujm-00440365$$DView record in HAL$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/21450336$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Pellerin, O.</creatorcontrib><creatorcontrib>Barral, F. G.</creatorcontrib><creatorcontrib>Lions, C.</creatorcontrib><creatorcontrib>Novelli, L.</creatorcontrib><creatorcontrib>Beregi, J. P.</creatorcontrib><creatorcontrib>Sapoval, M.</creatorcontrib><title>Early and Late Retrieval of the ALN Removable Vena Cava Filter: Results from a Multicenter Study</title><title>Cardiovascular and interventional radiology</title><addtitle>Cardiovasc Intervent Radiol</addtitle><addtitle>Cardiovasc Intervent Radiol</addtitle><description>Retrieval of removable inferior vena cava (IVC) filters in selected patients is widely practiced. The purpose of this multicenter study was to evaluate the feasibility and results of percutaneous removal of the ALN removable filter in a large patient cohort. Between November 2003 and June 2006, 123 consecutive patients were referred for percutaneous extraction of the ALN filter at three centers. The ALN filter is a removable filter that can be implanted through a femoral/jugular vein approach and extracted by the jugular vein approach. Filter removal was attempted after an implantation period of 93 ± 15 days (range, 6–722 days) through the right internal jugular vein approach using the dedicated extraction kit after control inferior vena cavography. Following filter removal, vena cavograms were obtained in all patients. Successful extraction was achieved in all but one case. Among these successful retrievals, additional manipulation using a femoral approach was needed when the apex of the filter was close to the IVC wall in two patients. No immediate IVC complications were observed according to the postimplantation cavography. Neither technical nor clinical differences between early and late filter retrieval were noticed. Our data confirm the safety of ALN filter retrieval up to 722 days after implantation. In infrequent cases, additional endovenous filter manipulation is needed to facilitate extraction.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>BLOOD VESSELS</subject><subject>BODY</subject><subject>Cardiology</subject><subject>CARDIOVASCULAR SYSTEM</subject><subject>Clinical Investigation</subject><subject>Device Removal</subject><subject>Device Removal - methods</subject><subject>Equipment Design</subject><subject>Equipment Safety</subject><subject>EXTRACTION</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>FILTERS</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Imaging</subject><subject>Life Sciences</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Nuclear Medicine</subject><subject>ORGANS</subject><subject>Pharmaceutical sciences</subject><subject>Pharmacology</subject><subject>Pulmonary Embolism</subject><subject>Pulmonary Embolism - etiology</subject><subject>Pulmonary Embolism - prevention & control</subject><subject>Radiography, Interventional</subject><subject>Radiology</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>REMOVAL</subject><subject>Retrospective Studies</subject><subject>Risk Assessment</subject><subject>SEPARATION PROCESSES</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Ultrasound</subject><subject>VEINS</subject><subject>Vena Cava Filters</subject><subject>Vena Cava, Inferior</subject><subject>Vena Cava, Inferior - diagnostic imaging</subject><subject>Vena Cava, Inferior - surgery</subject><subject>Venous Thrombosis</subject><subject>Venous Thrombosis - complications</subject><subject>Venous Thrombosis - diagnostic imaging</subject><subject>Venous Thrombosis - surgery</subject><issn>0174-1551</issn><issn>1432-086X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kVuLFDEQhYMo7uzqD_BFgoLgQ2vl1kn7Ngx7EVoFb_gW00na6aEva5Iedv69GXpwQfApVM5Xp6o4CD0j8IYAyLcRgEooAFRRMSGLuwdoRTijBajyx0O0AiJ5QYQgZ-g8xh0AEYqKx-iMKF4xRckK_bw0oT9gMzpcm-TxZ59C5_emx1OL09bjdf0xfw7T3jS9x9_9aPDG7A2-6vrkw7usxblPEbdhGrDBH3LRWT9mDX9Jszs8QY9a00f_9PReoG9Xl183N0X96fr9Zl0XllcyFc5WUhrOHVipaMslU54z51oPpjXATGuJck1LKq8aSZylRDRMtI2E0pUC2AV6ufhOMXU62i55u7XTOHqbNCU8I6zM1OuF2ppe34ZuMOGgJ9Ppm3Wt592gATgHVoo9yeyrhb0N0-_Zx6SHLlrf92b00xx1WQlOBFMZfPEPuJvmMOZrNaWSyZLJI0QWyIYpxuDbv-MJ6GOaekkzb6D0MU19l3uen4znZvDuvuMUXwboAsQsjb98uJ_8f9c_yRiocQ</recordid><startdate>20080901</startdate><enddate>20080901</enddate><creator>Pellerin, O.</creator><creator>Barral, F. G.</creator><creator>Lions, C.</creator><creator>Novelli, L.</creator><creator>Beregi, J. P.</creator><creator>Sapoval, M.</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><general>Cardiovascular and Interventional Radiological Society of Europe (CIRSE)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>1XC</scope><scope>OTOTI</scope></search><sort><creationdate>20080901</creationdate><title>Early and Late Retrieval of the ALN Removable Vena Cava Filter: Results from a Multicenter Study</title><author>Pellerin, O. ; Barral, F. G. ; Lions, C. ; Novelli, L. ; Beregi, J. P. ; Sapoval, M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c497t-dc977a44d0c782f4738e43ddfe0afa03afc18dbf19e8b71dc215b35fb706d6503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>BLOOD VESSELS</topic><topic>BODY</topic><topic>Cardiology</topic><topic>CARDIOVASCULAR SYSTEM</topic><topic>Clinical Investigation</topic><topic>Device Removal</topic><topic>Device Removal - methods</topic><topic>Equipment Design</topic><topic>Equipment Safety</topic><topic>EXTRACTION</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>FILTERS</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Imaging</topic><topic>Life Sciences</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Nuclear Medicine</topic><topic>ORGANS</topic><topic>Pharmaceutical sciences</topic><topic>Pharmacology</topic><topic>Pulmonary Embolism</topic><topic>Pulmonary Embolism - etiology</topic><topic>Pulmonary Embolism - prevention & control</topic><topic>Radiography, Interventional</topic><topic>Radiology</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>REMOVAL</topic><topic>Retrospective Studies</topic><topic>Risk Assessment</topic><topic>SEPARATION PROCESSES</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Ultrasound</topic><topic>VEINS</topic><topic>Vena Cava Filters</topic><topic>Vena Cava, Inferior</topic><topic>Vena Cava, Inferior - diagnostic imaging</topic><topic>Vena Cava, Inferior - surgery</topic><topic>Venous Thrombosis</topic><topic>Venous Thrombosis - complications</topic><topic>Venous Thrombosis - diagnostic imaging</topic><topic>Venous Thrombosis - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pellerin, O.</creatorcontrib><creatorcontrib>Barral, F. G.</creatorcontrib><creatorcontrib>Lions, C.</creatorcontrib><creatorcontrib>Novelli, L.</creatorcontrib><creatorcontrib>Beregi, J. P.</creatorcontrib><creatorcontrib>Sapoval, M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>OSTI.GOV</collection><jtitle>Cardiovascular and interventional radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pellerin, O.</au><au>Barral, F. G.</au><au>Lions, C.</au><au>Novelli, L.</au><au>Beregi, J. P.</au><au>Sapoval, M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Early and Late Retrieval of the ALN Removable Vena Cava Filter: Results from a Multicenter Study</atitle><jtitle>Cardiovascular and interventional radiology</jtitle><stitle>Cardiovasc Intervent Radiol</stitle><addtitle>Cardiovasc Intervent Radiol</addtitle><date>2008-09-01</date><risdate>2008</risdate><volume>31</volume><issue>5</issue><spage>889</spage><epage>896</epage><pages>889-896</pages><issn>0174-1551</issn><eissn>1432-086X</eissn><abstract>Retrieval of removable inferior vena cava (IVC) filters in selected patients is widely practiced. The purpose of this multicenter study was to evaluate the feasibility and results of percutaneous removal of the ALN removable filter in a large patient cohort. Between November 2003 and June 2006, 123 consecutive patients were referred for percutaneous extraction of the ALN filter at three centers. The ALN filter is a removable filter that can be implanted through a femoral/jugular vein approach and extracted by the jugular vein approach. Filter removal was attempted after an implantation period of 93 ± 15 days (range, 6–722 days) through the right internal jugular vein approach using the dedicated extraction kit after control inferior vena cavography. Following filter removal, vena cavograms were obtained in all patients. Successful extraction was achieved in all but one case. Among these successful retrievals, additional manipulation using a femoral approach was needed when the apex of the filter was close to the IVC wall in two patients. No immediate IVC complications were observed according to the postimplantation cavography. Neither technical nor clinical differences between early and late filter retrieval were noticed. Our data confirm the safety of ALN filter retrieval up to 722 days after implantation. In infrequent cases, additional endovenous filter manipulation is needed to facilitate extraction.</abstract><cop>New York</cop><pub>Springer-Verlag</pub><pmid>18493821</pmid><doi>10.1007/s00270-008-9357-x</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0174-1551 |
| ispartof | Cardiovascular and interventional radiology, 2008-09, Vol.31 (5), p.889-896 |
| issn | 0174-1551 1432-086X |
| language | eng |
| recordid | cdi_osti_scitechconnect_21450336 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Aged Aged, 80 and over BLOOD VESSELS BODY Cardiology CARDIOVASCULAR SYSTEM Clinical Investigation Device Removal Device Removal - methods Equipment Design Equipment Safety EXTRACTION Feasibility Studies Female FILTERS Follow-Up Studies Humans Imaging Life Sciences Male Medicine Medicine & Public Health Middle Aged Nuclear Medicine ORGANS Pharmaceutical sciences Pharmacology Pulmonary Embolism Pulmonary Embolism - etiology Pulmonary Embolism - prevention & control Radiography, Interventional Radiology RADIOLOGY AND NUCLEAR MEDICINE REMOVAL Retrospective Studies Risk Assessment SEPARATION PROCESSES Time Factors Treatment Outcome Ultrasound VEINS Vena Cava Filters Vena Cava, Inferior Vena Cava, Inferior - diagnostic imaging Vena Cava, Inferior - surgery Venous Thrombosis Venous Thrombosis - complications Venous Thrombosis - diagnostic imaging Venous Thrombosis - surgery |
| title | Early and Late Retrieval of the ALN Removable Vena Cava Filter: Results from a Multicenter Study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T23%3A33%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_osti_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Early%20and%20Late%20Retrieval%20of%20the%20ALN%20Removable%20Vena%20Cava%20Filter:%20Results%20from%20a%20Multicenter%20Study&rft.jtitle=Cardiovascular%20and%20interventional%20radiology&rft.au=Pellerin,%20O.&rft.date=2008-09-01&rft.volume=31&rft.issue=5&rft.spage=889&rft.epage=896&rft.pages=889-896&rft.issn=0174-1551&rft.eissn=1432-086X&rft_id=info:doi/10.1007/s00270-008-9357-x&rft_dat=%3Cproquest_osti_%3E69541538%3C/proquest_osti_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=227376378&rft_id=info:pmid/18493821&rfr_iscdi=true |