Toxicity Analysis of Postoperative Image-Guided Intensity-Modulated Radiotherapy for Prostate Cancer
Purpose To report on the acute and late gastrointestinal (GI) and genitourinary (GU) toxicity associated with a unique technique of image-guided radiotherapy (IGRT) in patients undergoing postprostatectomy irradiation. Methods and Materials Fifty patients were treated with intensity-modulated radiat...
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| creator | Nath, Sameer K., B.A Sandhu, Ajay P., M.D Rose, Brent S., B.S Simpson, Daniel R., B.S Nobiensky, Polly D., R.N Wang, Jia-Zhu, Ph.D Millard, Fred, M.D Kane, Christopher J., M.D Parsons, J. Kellogg, M.D Mundt, Arno J., M.D |
| description | Purpose To report on the acute and late gastrointestinal (GI) and genitourinary (GU) toxicity associated with a unique technique of image-guided radiotherapy (IGRT) in patients undergoing postprostatectomy irradiation. Methods and Materials Fifty patients were treated with intensity-modulated radiation therapy (IMRT) after radical prostatectomy. Daily image guidance was performed to localize the prostate bed using kilovoltage imaging or cone-beam computed tomography. The median prescription dose was 68 Gy (range, 62–68 Gy). Toxicity was graded every 3 to 6 months according to the Common Terminology Criteria for Adverse Events version 3.0. Results The median follow-up was 24 months (range, 13–38 months). Grade 2 acute GI and GU events occurred in 4 patients (8%) and 7 patients (14%), respectively. No Grade 3 or higher acute GI or GU toxicities were observed. Late Grade 2 GI and GU events occurred in 1 patient (2%) and 8 patients (16%), respectively. Only a single (2%) Grade 3 or higher late toxicity was observed. Conclusions Image-guided IMRT in the postprostatectomy setting is associated with a low frequency of acute and late GI/GU toxicity. These results compare more favorably to radiotherapy techniques that do not use in-room image-guidance, suggesting that daily prostate bed localization may reduce the incidence of adverse events in patients undergoing postprostatectomy irradiation. |
| doi_str_mv | 10.1016/j.ijrobp.2009.08.023 |
| format | Article |
| fullrecord | <record><control><sourceid>pubmed_osti_</sourceid><recordid>TN_cdi_osti_scitechconnect_21436184</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0360301609029745</els_id><sourcerecordid>19939580</sourcerecordid><originalsourceid>FETCH-LOGICAL-c540t-49e36a090d5e0a7f4cde7d046df6e0ba883e4865dc4bc45cdd5ba3cec36167303</originalsourceid><addsrcrecordid>eNqFklGL1TAQhYso7nX1H4gUxMfWSZOm7YuwXHS9sOKiK_gW0mTqpvY2Jeld7L93Si8KvvgUSL4zc-ZkkuQlg5wBk2_73PXBt1NeADQ51DkU_FGyY3XVZLwsvz9OdsAlZJzgi-RZjD0AMFaJp8kFaxrelDXsEnvnfznj5iW9GvWwRBdT36W3Ps5-wqBn94Dp4ah_YHZ9chZtehhnHCMJsk_engY9090XbZ2f74mflrTzIb0NVICe0r0eDYbnyZNODxFfnM_L5NuH93f7j9nN5-vD_uomM6WAORMNcqmhAVsi6KoTxmJlQUjbSYRW1zVHUcvSGtEaURpry1Zzg4ZLJisO_DJ5vdWl7k5FGgvNvfHjiGZWBRPE1YIosVGGXMaAnZqCO-qwKAZqjVb1aotWrdEqqBVFS7JXm2w6tUe0f0XnLAl4cwZ0NHroAs3u4h-u4IUUUjbEvds4pCgeHIbVKVJO1oXVqPXuf07-LWAGNzrq-RMXjL0_BfrLqJiKhQL1dV2DdQso2aKpRMl_A90ar7M</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Toxicity Analysis of Postoperative Image-Guided Intensity-Modulated Radiotherapy for Prostate Cancer</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Nath, Sameer K., B.A ; Sandhu, Ajay P., M.D ; Rose, Brent S., B.S ; Simpson, Daniel R., B.S ; Nobiensky, Polly D., R.N ; Wang, Jia-Zhu, Ph.D ; Millard, Fred, M.D ; Kane, Christopher J., M.D ; Parsons, J. Kellogg, M.D ; Mundt, Arno J., M.D</creator><creatorcontrib>Nath, Sameer K., B.A ; Sandhu, Ajay P., M.D ; Rose, Brent S., B.S ; Simpson, Daniel R., B.S ; Nobiensky, Polly D., R.N ; Wang, Jia-Zhu, Ph.D ; Millard, Fred, M.D ; Kane, Christopher J., M.D ; Parsons, J. Kellogg, M.D ; Mundt, Arno J., M.D</creatorcontrib><description>Purpose To report on the acute and late gastrointestinal (GI) and genitourinary (GU) toxicity associated with a unique technique of image-guided radiotherapy (IGRT) in patients undergoing postprostatectomy irradiation. Methods and Materials Fifty patients were treated with intensity-modulated radiation therapy (IMRT) after radical prostatectomy. Daily image guidance was performed to localize the prostate bed using kilovoltage imaging or cone-beam computed tomography. The median prescription dose was 68 Gy (range, 62–68 Gy). Toxicity was graded every 3 to 6 months according to the Common Terminology Criteria for Adverse Events version 3.0. Results The median follow-up was 24 months (range, 13–38 months). Grade 2 acute GI and GU events occurred in 4 patients (8%) and 7 patients (14%), respectively. No Grade 3 or higher acute GI or GU toxicities were observed. Late Grade 2 GI and GU events occurred in 1 patient (2%) and 8 patients (16%), respectively. Only a single (2%) Grade 3 or higher late toxicity was observed. Conclusions Image-guided IMRT in the postprostatectomy setting is associated with a low frequency of acute and late GI/GU toxicity. These results compare more favorably to radiotherapy techniques that do not use in-room image-guidance, suggesting that daily prostate bed localization may reduce the incidence of adverse events in patients undergoing postprostatectomy irradiation.</description><identifier>ISSN: 0360-3016</identifier><identifier>EISSN: 1879-355X</identifier><identifier>DOI: 10.1016/j.ijrobp.2009.08.023</identifier><identifier>PMID: 19939580</identifier><identifier>CODEN: IOBPD3</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adjuvant ; Aged ; Biological and medical sciences ; BODY ; COMPUTERIZED TOMOGRAPHY ; Cone-Beam Computed Tomography ; DIAGNOSTIC TECHNIQUES ; DISEASES ; Follow-Up Studies ; Gastrointestinal Tract - radiation effects ; GLANDS ; Gynecology. Andrology. Obstetrics ; Hematology, Oncology and Palliative Medicine ; Humans ; Image-guided radiotherapy ; Intensity-modulated radiation therapy (IMRT) ; Male ; Male genital diseases ; MALE GENITALS ; Medical sciences ; MEDICINE ; Middle Aged ; Multivariate Analysis ; NEOPLASMS ; Nephrology. Urinary tract diseases ; NUCLEAR MEDICINE ; ORGANS ; Postoperative Period ; PROSTATE ; Prostate cancer ; Prostatectomy ; Prostatic Neoplasms - pathology ; Prostatic Neoplasms - radiotherapy ; Prostatic Neoplasms - surgery ; Radiation Injuries - pathology ; RADIOLOGY ; RADIOLOGY AND NUCLEAR MEDICINE ; RADIOTHERAPY ; Radiotherapy Dosage ; Radiotherapy, Adjuvant - methods ; Radiotherapy, Intensity-Modulated - adverse effects ; Radiotherapy, Intensity-Modulated - methods ; Salvage ; Salvage Therapy - methods ; Severity of Illness Index ; THERAPY ; TOMOGRAPHY ; TOXICITY ; Tumors ; Tumors of the urinary system ; Urinary tract. Prostate gland ; Urogenital System - radiation effects</subject><ispartof>International journal of radiation oncology, biology, physics, 2010-10, Vol.78 (2), p.435-441</ispartof><rights>Elsevier Inc.</rights><rights>2010 Elsevier Inc.</rights><rights>2015 INIST-CNRS</rights><rights>2010 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c540t-49e36a090d5e0a7f4cde7d046df6e0ba883e4865dc4bc45cdd5ba3cec36167303</citedby><cites>FETCH-LOGICAL-c540t-49e36a090d5e0a7f4cde7d046df6e0ba883e4865dc4bc45cdd5ba3cec36167303</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0360301609029745$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23264669$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19939580$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/21436184$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Nath, Sameer K., B.A</creatorcontrib><creatorcontrib>Sandhu, Ajay P., M.D</creatorcontrib><creatorcontrib>Rose, Brent S., B.S</creatorcontrib><creatorcontrib>Simpson, Daniel R., B.S</creatorcontrib><creatorcontrib>Nobiensky, Polly D., R.N</creatorcontrib><creatorcontrib>Wang, Jia-Zhu, Ph.D</creatorcontrib><creatorcontrib>Millard, Fred, M.D</creatorcontrib><creatorcontrib>Kane, Christopher J., M.D</creatorcontrib><creatorcontrib>Parsons, J. Kellogg, M.D</creatorcontrib><creatorcontrib>Mundt, Arno J., M.D</creatorcontrib><title>Toxicity Analysis of Postoperative Image-Guided Intensity-Modulated Radiotherapy for Prostate Cancer</title><title>International journal of radiation oncology, biology, physics</title><addtitle>Int J Radiat Oncol Biol Phys</addtitle><description>Purpose To report on the acute and late gastrointestinal (GI) and genitourinary (GU) toxicity associated with a unique technique of image-guided radiotherapy (IGRT) in patients undergoing postprostatectomy irradiation. Methods and Materials Fifty patients were treated with intensity-modulated radiation therapy (IMRT) after radical prostatectomy. Daily image guidance was performed to localize the prostate bed using kilovoltage imaging or cone-beam computed tomography. The median prescription dose was 68 Gy (range, 62–68 Gy). Toxicity was graded every 3 to 6 months according to the Common Terminology Criteria for Adverse Events version 3.0. Results The median follow-up was 24 months (range, 13–38 months). Grade 2 acute GI and GU events occurred in 4 patients (8%) and 7 patients (14%), respectively. No Grade 3 or higher acute GI or GU toxicities were observed. Late Grade 2 GI and GU events occurred in 1 patient (2%) and 8 patients (16%), respectively. Only a single (2%) Grade 3 or higher late toxicity was observed. Conclusions Image-guided IMRT in the postprostatectomy setting is associated with a low frequency of acute and late GI/GU toxicity. These results compare more favorably to radiotherapy techniques that do not use in-room image-guidance, suggesting that daily prostate bed localization may reduce the incidence of adverse events in patients undergoing postprostatectomy irradiation.</description><subject>Adjuvant</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>BODY</subject><subject>COMPUTERIZED TOMOGRAPHY</subject><subject>Cone-Beam Computed Tomography</subject><subject>DIAGNOSTIC TECHNIQUES</subject><subject>DISEASES</subject><subject>Follow-Up Studies</subject><subject>Gastrointestinal Tract - radiation effects</subject><subject>GLANDS</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Hematology, Oncology and Palliative Medicine</subject><subject>Humans</subject><subject>Image-guided radiotherapy</subject><subject>Intensity-modulated radiation therapy (IMRT)</subject><subject>Male</subject><subject>Male genital diseases</subject><subject>MALE GENITALS</subject><subject>Medical sciences</subject><subject>MEDICINE</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>NEOPLASMS</subject><subject>Nephrology. Urinary tract diseases</subject><subject>NUCLEAR MEDICINE</subject><subject>ORGANS</subject><subject>Postoperative Period</subject><subject>PROSTATE</subject><subject>Prostate cancer</subject><subject>Prostatectomy</subject><subject>Prostatic Neoplasms - pathology</subject><subject>Prostatic Neoplasms - radiotherapy</subject><subject>Prostatic Neoplasms - surgery</subject><subject>Radiation Injuries - pathology</subject><subject>RADIOLOGY</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>RADIOTHERAPY</subject><subject>Radiotherapy Dosage</subject><subject>Radiotherapy, Adjuvant - methods</subject><subject>Radiotherapy, Intensity-Modulated - adverse effects</subject><subject>Radiotherapy, Intensity-Modulated - methods</subject><subject>Salvage</subject><subject>Salvage Therapy - methods</subject><subject>Severity of Illness Index</subject><subject>THERAPY</subject><subject>TOMOGRAPHY</subject><subject>TOXICITY</subject><subject>Tumors</subject><subject>Tumors of the urinary system</subject><subject>Urinary tract. Prostate gland</subject><subject>Urogenital System - radiation effects</subject><issn>0360-3016</issn><issn>1879-355X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFklGL1TAQhYso7nX1H4gUxMfWSZOm7YuwXHS9sOKiK_gW0mTqpvY2Jeld7L93Si8KvvgUSL4zc-ZkkuQlg5wBk2_73PXBt1NeADQ51DkU_FGyY3XVZLwsvz9OdsAlZJzgi-RZjD0AMFaJp8kFaxrelDXsEnvnfznj5iW9GvWwRBdT36W3Ps5-wqBn94Dp4ah_YHZ9chZtehhnHCMJsk_engY9090XbZ2f74mflrTzIb0NVICe0r0eDYbnyZNODxFfnM_L5NuH93f7j9nN5-vD_uomM6WAORMNcqmhAVsi6KoTxmJlQUjbSYRW1zVHUcvSGtEaURpry1Zzg4ZLJisO_DJ5vdWl7k5FGgvNvfHjiGZWBRPE1YIosVGGXMaAnZqCO-qwKAZqjVb1aotWrdEqqBVFS7JXm2w6tUe0f0XnLAl4cwZ0NHroAs3u4h-u4IUUUjbEvds4pCgeHIbVKVJO1oXVqPXuf07-LWAGNzrq-RMXjL0_BfrLqJiKhQL1dV2DdQso2aKpRMl_A90ar7M</recordid><startdate>20101001</startdate><enddate>20101001</enddate><creator>Nath, Sameer K., B.A</creator><creator>Sandhu, Ajay P., M.D</creator><creator>Rose, Brent S., B.S</creator><creator>Simpson, Daniel R., B.S</creator><creator>Nobiensky, Polly D., R.N</creator><creator>Wang, Jia-Zhu, Ph.D</creator><creator>Millard, Fred, M.D</creator><creator>Kane, Christopher J., M.D</creator><creator>Parsons, J. Kellogg, M.D</creator><creator>Mundt, Arno J., M.D</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>20101001</creationdate><title>Toxicity Analysis of Postoperative Image-Guided Intensity-Modulated Radiotherapy for Prostate Cancer</title><author>Nath, Sameer K., B.A ; Sandhu, Ajay P., M.D ; Rose, Brent S., B.S ; Simpson, Daniel R., B.S ; Nobiensky, Polly D., R.N ; Wang, Jia-Zhu, Ph.D ; Millard, Fred, M.D ; Kane, Christopher J., M.D ; Parsons, J. Kellogg, M.D ; Mundt, Arno J., M.D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c540t-49e36a090d5e0a7f4cde7d046df6e0ba883e4865dc4bc45cdd5ba3cec36167303</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adjuvant</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>BODY</topic><topic>COMPUTERIZED TOMOGRAPHY</topic><topic>Cone-Beam Computed Tomography</topic><topic>DIAGNOSTIC TECHNIQUES</topic><topic>DISEASES</topic><topic>Follow-Up Studies</topic><topic>Gastrointestinal Tract - radiation effects</topic><topic>GLANDS</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Hematology, Oncology and Palliative Medicine</topic><topic>Humans</topic><topic>Image-guided radiotherapy</topic><topic>Intensity-modulated radiation therapy (IMRT)</topic><topic>Male</topic><topic>Male genital diseases</topic><topic>MALE GENITALS</topic><topic>Medical sciences</topic><topic>MEDICINE</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>NEOPLASMS</topic><topic>Nephrology. Urinary tract diseases</topic><topic>NUCLEAR MEDICINE</topic><topic>ORGANS</topic><topic>Postoperative Period</topic><topic>PROSTATE</topic><topic>Prostate cancer</topic><topic>Prostatectomy</topic><topic>Prostatic Neoplasms - pathology</topic><topic>Prostatic Neoplasms - radiotherapy</topic><topic>Prostatic Neoplasms - surgery</topic><topic>Radiation Injuries - pathology</topic><topic>RADIOLOGY</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>RADIOTHERAPY</topic><topic>Radiotherapy Dosage</topic><topic>Radiotherapy, Adjuvant - methods</topic><topic>Radiotherapy, Intensity-Modulated - adverse effects</topic><topic>Radiotherapy, Intensity-Modulated - methods</topic><topic>Salvage</topic><topic>Salvage Therapy - methods</topic><topic>Severity of Illness Index</topic><topic>THERAPY</topic><topic>TOMOGRAPHY</topic><topic>TOXICITY</topic><topic>Tumors</topic><topic>Tumors of the urinary system</topic><topic>Urinary tract. Prostate gland</topic><topic>Urogenital System - radiation effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nath, Sameer K., B.A</creatorcontrib><creatorcontrib>Sandhu, Ajay P., M.D</creatorcontrib><creatorcontrib>Rose, Brent S., B.S</creatorcontrib><creatorcontrib>Simpson, Daniel R., B.S</creatorcontrib><creatorcontrib>Nobiensky, Polly D., R.N</creatorcontrib><creatorcontrib>Wang, Jia-Zhu, Ph.D</creatorcontrib><creatorcontrib>Millard, Fred, M.D</creatorcontrib><creatorcontrib>Kane, Christopher J., M.D</creatorcontrib><creatorcontrib>Parsons, J. Kellogg, M.D</creatorcontrib><creatorcontrib>Mundt, Arno J., M.D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>International journal of radiation oncology, biology, physics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nath, Sameer K., B.A</au><au>Sandhu, Ajay P., M.D</au><au>Rose, Brent S., B.S</au><au>Simpson, Daniel R., B.S</au><au>Nobiensky, Polly D., R.N</au><au>Wang, Jia-Zhu, Ph.D</au><au>Millard, Fred, M.D</au><au>Kane, Christopher J., M.D</au><au>Parsons, J. Kellogg, M.D</au><au>Mundt, Arno J., M.D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Toxicity Analysis of Postoperative Image-Guided Intensity-Modulated Radiotherapy for Prostate Cancer</atitle><jtitle>International journal of radiation oncology, biology, physics</jtitle><addtitle>Int J Radiat Oncol Biol Phys</addtitle><date>2010-10-01</date><risdate>2010</risdate><volume>78</volume><issue>2</issue><spage>435</spage><epage>441</epage><pages>435-441</pages><issn>0360-3016</issn><eissn>1879-355X</eissn><coden>IOBPD3</coden><abstract>Purpose To report on the acute and late gastrointestinal (GI) and genitourinary (GU) toxicity associated with a unique technique of image-guided radiotherapy (IGRT) in patients undergoing postprostatectomy irradiation. Methods and Materials Fifty patients were treated with intensity-modulated radiation therapy (IMRT) after radical prostatectomy. Daily image guidance was performed to localize the prostate bed using kilovoltage imaging or cone-beam computed tomography. The median prescription dose was 68 Gy (range, 62–68 Gy). Toxicity was graded every 3 to 6 months according to the Common Terminology Criteria for Adverse Events version 3.0. Results The median follow-up was 24 months (range, 13–38 months). Grade 2 acute GI and GU events occurred in 4 patients (8%) and 7 patients (14%), respectively. No Grade 3 or higher acute GI or GU toxicities were observed. Late Grade 2 GI and GU events occurred in 1 patient (2%) and 8 patients (16%), respectively. Only a single (2%) Grade 3 or higher late toxicity was observed. Conclusions Image-guided IMRT in the postprostatectomy setting is associated with a low frequency of acute and late GI/GU toxicity. These results compare more favorably to radiotherapy techniques that do not use in-room image-guidance, suggesting that daily prostate bed localization may reduce the incidence of adverse events in patients undergoing postprostatectomy irradiation.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>19939580</pmid><doi>10.1016/j.ijrobp.2009.08.023</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0360-3016 |
| ispartof | International journal of radiation oncology, biology, physics, 2010-10, Vol.78 (2), p.435-441 |
| issn | 0360-3016 1879-355X |
| language | eng |
| recordid | cdi_osti_scitechconnect_21436184 |
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| subjects | Adjuvant Aged Biological and medical sciences BODY COMPUTERIZED TOMOGRAPHY Cone-Beam Computed Tomography DIAGNOSTIC TECHNIQUES DISEASES Follow-Up Studies Gastrointestinal Tract - radiation effects GLANDS Gynecology. Andrology. Obstetrics Hematology, Oncology and Palliative Medicine Humans Image-guided radiotherapy Intensity-modulated radiation therapy (IMRT) Male Male genital diseases MALE GENITALS Medical sciences MEDICINE Middle Aged Multivariate Analysis NEOPLASMS Nephrology. Urinary tract diseases NUCLEAR MEDICINE ORGANS Postoperative Period PROSTATE Prostate cancer Prostatectomy Prostatic Neoplasms - pathology Prostatic Neoplasms - radiotherapy Prostatic Neoplasms - surgery Radiation Injuries - pathology RADIOLOGY RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Radiotherapy Dosage Radiotherapy, Adjuvant - methods Radiotherapy, Intensity-Modulated - adverse effects Radiotherapy, Intensity-Modulated - methods Salvage Salvage Therapy - methods Severity of Illness Index THERAPY TOMOGRAPHY TOXICITY Tumors Tumors of the urinary system Urinary tract. Prostate gland Urogenital System - radiation effects |
| title | Toxicity Analysis of Postoperative Image-Guided Intensity-Modulated Radiotherapy for Prostate Cancer |
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