Assessment of Bladder Motion for Clinical Radiotherapy Practice Using Cine–Magnetic Resonance Imaging
Purpose Organ motion is recognized as the principal source of inaccuracy in bladder radiotherapy (RT), but there is currently little information on intrafraction bladder motion. Methods and Materials We used cine–magnetic resonance imaging (cine-MRI) to study bladder motion relevant to intrafraction...
Gespeichert in:
| Veröffentlicht in: | International journal of radiation oncology, biology, physics biology, physics, 2009-11, Vol.75 (3), p.664-671 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 671 |
|---|---|
| container_issue | 3 |
| container_start_page | 664 |
| container_title | International journal of radiation oncology, biology, physics |
| container_volume | 75 |
| creator | McBain, Catherine A., F.R.C.R Khoo, Vincent S., F.R.C.R Buckley, David L., Ph.D Sykes, Jonathan S., M.Sc Green, Melanie M., Ph.D Cowan, Richard A., F.R.C.R Hutchinson, Charles E., F.R.C.R Moore, Christopher J., Ph.D Price, Patricia M., F.R.C.R |
| description | Purpose Organ motion is recognized as the principal source of inaccuracy in bladder radiotherapy (RT), but there is currently little information on intrafraction bladder motion. Methods and Materials We used cine–magnetic resonance imaging (cine-MRI) to study bladder motion relevant to intrafraction RT delivery. On two occasions, a 28 minute cine-MRI sequence was acquired from 10 bladder cancer patients and 5 control participants immediately after bladder emptying, after abstinence from drinking for the preceding hour. From the resulting cine sequences, bladder motion was subjectively assessed. To quantify bladder motion, the bladder was contoured in imaging volume sets at 0, 14, and 28 min to measure changes to bladder volumes, wall displacements, and center of gravity (COG) over time. Results The dominant source of bladder motion during imaging was bladder filling (up to 101% volume increase); rectal and small bowel movements were transient, with minimal impact. Bladder volume changes were similar for all participants. However for bladder cancer patients, wall displacements were larger (up to 58 mm), less symmetrical, and more variable compared with nondiseased control bladders. Conclusions Significant and individualized intrafraction bladder wall displacements may occur during bladder RT delivery. This important source of inaccuracy should be incorporated into treatment planning and verification. |
| doi_str_mv | 10.1016/j.ijrobp.2008.11.040 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_osti_</sourceid><recordid>TN_cdi_osti_scitechconnect_21362198</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0360301608038534</els_id><sourcerecordid>67677754</sourcerecordid><originalsourceid>FETCH-LOGICAL-c540t-589bf1e2f5659eda92d82139d9b31f6a70d125ffad23572b38b86fdb0b0a48813</originalsourceid><addsrcrecordid>eNqFkt-K1DAUh4so7rj6BiIFwbvWnKZp0xthHfyzsIuyuuBdSJOT2dQ2GZOOMHe-g2_ok5jSAcGbvQok3_mFc76TZc-BlECgeT2Udgi-35cVIbwEKElNHmQb4G1XUMa-Pcw2hDakoAk-y57EOBBCANr6cXYGXd3SlsMm213EiDFO6Obcm_ztKLXGkF_72XqXGx_y7WidVXLMb6S2fr7DIPfH_HOQarYK89to3S7fWod_fv2-ljuH6Tq_weiddOn9cpK7RDzNHhk5Rnx2Os-z2_fvvm4_FlefPlxuL64KxWoyF4x3vQGsDGtYh1p2leYV0E53PQXTyJZoqJgxUleUtVVPec8bo3vSE1lzDvQ8e7nm-jhbEZWdUd0p7xyqWaSkpoKOJ-rVSu2D_3HAOIvJRoXjKB36QxRN27Rty-p7wSoNlNfAElivoAo-xoBG7IOdZDgKIGLxJQax-hKLLwEgkq9U9uKUf-gn1P-KToIS8GYFMA3tp8Ww9IRpsNqGpSXt7X0__B-gTkK_4xHj4A_BJSECRKwEEV-WnVlWhnBCOaM1_Qv-kr35</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>21178415</pqid></control><display><type>article</type><title>Assessment of Bladder Motion for Clinical Radiotherapy Practice Using Cine–Magnetic Resonance Imaging</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>McBain, Catherine A., F.R.C.R ; Khoo, Vincent S., F.R.C.R ; Buckley, David L., Ph.D ; Sykes, Jonathan S., M.Sc ; Green, Melanie M., Ph.D ; Cowan, Richard A., F.R.C.R ; Hutchinson, Charles E., F.R.C.R ; Moore, Christopher J., Ph.D ; Price, Patricia M., F.R.C.R</creator><creatorcontrib>McBain, Catherine A., F.R.C.R ; Khoo, Vincent S., F.R.C.R ; Buckley, David L., Ph.D ; Sykes, Jonathan S., M.Sc ; Green, Melanie M., Ph.D ; Cowan, Richard A., F.R.C.R ; Hutchinson, Charles E., F.R.C.R ; Moore, Christopher J., Ph.D ; Price, Patricia M., F.R.C.R</creatorcontrib><description>Purpose Organ motion is recognized as the principal source of inaccuracy in bladder radiotherapy (RT), but there is currently little information on intrafraction bladder motion. Methods and Materials We used cine–magnetic resonance imaging (cine-MRI) to study bladder motion relevant to intrafraction RT delivery. On two occasions, a 28 minute cine-MRI sequence was acquired from 10 bladder cancer patients and 5 control participants immediately after bladder emptying, after abstinence from drinking for the preceding hour. From the resulting cine sequences, bladder motion was subjectively assessed. To quantify bladder motion, the bladder was contoured in imaging volume sets at 0, 14, and 28 min to measure changes to bladder volumes, wall displacements, and center of gravity (COG) over time. Results The dominant source of bladder motion during imaging was bladder filling (up to 101% volume increase); rectal and small bowel movements were transient, with minimal impact. Bladder volume changes were similar for all participants. However for bladder cancer patients, wall displacements were larger (up to 58 mm), less symmetrical, and more variable compared with nondiseased control bladders. Conclusions Significant and individualized intrafraction bladder wall displacements may occur during bladder RT delivery. This important source of inaccuracy should be incorporated into treatment planning and verification.</description><identifier>ISSN: 0360-3016</identifier><identifier>EISSN: 1879-355X</identifier><identifier>DOI: 10.1016/j.ijrobp.2008.11.040</identifier><identifier>PMID: 19473781</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Aged ; BLADDER ; Bladder cancer ; BODY ; Case-Control Studies ; Cine-MRI ; DIAGNOSTIC TECHNIQUES ; DISEASES ; Dose Fractionation ; Female ; Hematology, Oncology and Palliative Medicine ; Humans ; Intestine, Small - anatomy & histology ; Intrafraction motion ; Magnetic Resonance Imaging, Cine ; Male ; MEDICINE ; Middle Aged ; MOTION ; Movement ; NEOPLASMS ; NMR IMAGING ; NUCLEAR MEDICINE ; Organ Size ; ORGANS ; Prospective Studies ; RADIOLOGY ; RADIOLOGY AND NUCLEAR MEDICINE ; RADIOTHERAPY ; Rectum - anatomy & histology ; Reproducibility of Results ; THERAPY ; Tumor Burden ; Urinary Bladder - anatomy & histology ; Urinary Bladder Neoplasms - pathology ; Urinary Bladder Neoplasms - radiotherapy ; URINARY TRACT ; Urine</subject><ispartof>International journal of radiation oncology, biology, physics, 2009-11, Vol.75 (3), p.664-671</ispartof><rights>Elsevier Inc.</rights><rights>2009 Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c540t-589bf1e2f5659eda92d82139d9b31f6a70d125ffad23572b38b86fdb0b0a48813</citedby><cites>FETCH-LOGICAL-c540t-589bf1e2f5659eda92d82139d9b31f6a70d125ffad23572b38b86fdb0b0a48813</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0360301608038534$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19473781$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/21362198$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>McBain, Catherine A., F.R.C.R</creatorcontrib><creatorcontrib>Khoo, Vincent S., F.R.C.R</creatorcontrib><creatorcontrib>Buckley, David L., Ph.D</creatorcontrib><creatorcontrib>Sykes, Jonathan S., M.Sc</creatorcontrib><creatorcontrib>Green, Melanie M., Ph.D</creatorcontrib><creatorcontrib>Cowan, Richard A., F.R.C.R</creatorcontrib><creatorcontrib>Hutchinson, Charles E., F.R.C.R</creatorcontrib><creatorcontrib>Moore, Christopher J., Ph.D</creatorcontrib><creatorcontrib>Price, Patricia M., F.R.C.R</creatorcontrib><title>Assessment of Bladder Motion for Clinical Radiotherapy Practice Using Cine–Magnetic Resonance Imaging</title><title>International journal of radiation oncology, biology, physics</title><addtitle>Int J Radiat Oncol Biol Phys</addtitle><description>Purpose Organ motion is recognized as the principal source of inaccuracy in bladder radiotherapy (RT), but there is currently little information on intrafraction bladder motion. Methods and Materials We used cine–magnetic resonance imaging (cine-MRI) to study bladder motion relevant to intrafraction RT delivery. On two occasions, a 28 minute cine-MRI sequence was acquired from 10 bladder cancer patients and 5 control participants immediately after bladder emptying, after abstinence from drinking for the preceding hour. From the resulting cine sequences, bladder motion was subjectively assessed. To quantify bladder motion, the bladder was contoured in imaging volume sets at 0, 14, and 28 min to measure changes to bladder volumes, wall displacements, and center of gravity (COG) over time. Results The dominant source of bladder motion during imaging was bladder filling (up to 101% volume increase); rectal and small bowel movements were transient, with minimal impact. Bladder volume changes were similar for all participants. However for bladder cancer patients, wall displacements were larger (up to 58 mm), less symmetrical, and more variable compared with nondiseased control bladders. Conclusions Significant and individualized intrafraction bladder wall displacements may occur during bladder RT delivery. This important source of inaccuracy should be incorporated into treatment planning and verification.</description><subject>Aged</subject><subject>BLADDER</subject><subject>Bladder cancer</subject><subject>BODY</subject><subject>Case-Control Studies</subject><subject>Cine-MRI</subject><subject>DIAGNOSTIC TECHNIQUES</subject><subject>DISEASES</subject><subject>Dose Fractionation</subject><subject>Female</subject><subject>Hematology, Oncology and Palliative Medicine</subject><subject>Humans</subject><subject>Intestine, Small - anatomy & histology</subject><subject>Intrafraction motion</subject><subject>Magnetic Resonance Imaging, Cine</subject><subject>Male</subject><subject>MEDICINE</subject><subject>Middle Aged</subject><subject>MOTION</subject><subject>Movement</subject><subject>NEOPLASMS</subject><subject>NMR IMAGING</subject><subject>NUCLEAR MEDICINE</subject><subject>Organ Size</subject><subject>ORGANS</subject><subject>Prospective Studies</subject><subject>RADIOLOGY</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>RADIOTHERAPY</subject><subject>Rectum - anatomy & histology</subject><subject>Reproducibility of Results</subject><subject>THERAPY</subject><subject>Tumor Burden</subject><subject>Urinary Bladder - anatomy & histology</subject><subject>Urinary Bladder Neoplasms - pathology</subject><subject>Urinary Bladder Neoplasms - radiotherapy</subject><subject>URINARY TRACT</subject><subject>Urine</subject><issn>0360-3016</issn><issn>1879-355X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkt-K1DAUh4so7rj6BiIFwbvWnKZp0xthHfyzsIuyuuBdSJOT2dQ2GZOOMHe-g2_ok5jSAcGbvQok3_mFc76TZc-BlECgeT2Udgi-35cVIbwEKElNHmQb4G1XUMa-Pcw2hDakoAk-y57EOBBCANr6cXYGXd3SlsMm213EiDFO6Obcm_ztKLXGkF_72XqXGx_y7WidVXLMb6S2fr7DIPfH_HOQarYK89to3S7fWod_fv2-ljuH6Tq_weiddOn9cpK7RDzNHhk5Rnx2Os-z2_fvvm4_FlefPlxuL64KxWoyF4x3vQGsDGtYh1p2leYV0E53PQXTyJZoqJgxUleUtVVPec8bo3vSE1lzDvQ8e7nm-jhbEZWdUd0p7xyqWaSkpoKOJ-rVSu2D_3HAOIvJRoXjKB36QxRN27Rty-p7wSoNlNfAElivoAo-xoBG7IOdZDgKIGLxJQax-hKLLwEgkq9U9uKUf-gn1P-KToIS8GYFMA3tp8Ww9IRpsNqGpSXt7X0__B-gTkK_4xHj4A_BJSECRKwEEV-WnVlWhnBCOaM1_Qv-kr35</recordid><startdate>20091101</startdate><enddate>20091101</enddate><creator>McBain, Catherine A., F.R.C.R</creator><creator>Khoo, Vincent S., F.R.C.R</creator><creator>Buckley, David L., Ph.D</creator><creator>Sykes, Jonathan S., M.Sc</creator><creator>Green, Melanie M., Ph.D</creator><creator>Cowan, Richard A., F.R.C.R</creator><creator>Hutchinson, Charles E., F.R.C.R</creator><creator>Moore, Christopher J., Ph.D</creator><creator>Price, Patricia M., F.R.C.R</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U7</scope><scope>C1K</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>20091101</creationdate><title>Assessment of Bladder Motion for Clinical Radiotherapy Practice Using Cine–Magnetic Resonance Imaging</title><author>McBain, Catherine A., F.R.C.R ; Khoo, Vincent S., F.R.C.R ; Buckley, David L., Ph.D ; Sykes, Jonathan S., M.Sc ; Green, Melanie M., Ph.D ; Cowan, Richard A., F.R.C.R ; Hutchinson, Charles E., F.R.C.R ; Moore, Christopher J., Ph.D ; Price, Patricia M., F.R.C.R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c540t-589bf1e2f5659eda92d82139d9b31f6a70d125ffad23572b38b86fdb0b0a48813</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Aged</topic><topic>BLADDER</topic><topic>Bladder cancer</topic><topic>BODY</topic><topic>Case-Control Studies</topic><topic>Cine-MRI</topic><topic>DIAGNOSTIC TECHNIQUES</topic><topic>DISEASES</topic><topic>Dose Fractionation</topic><topic>Female</topic><topic>Hematology, Oncology and Palliative Medicine</topic><topic>Humans</topic><topic>Intestine, Small - anatomy & histology</topic><topic>Intrafraction motion</topic><topic>Magnetic Resonance Imaging, Cine</topic><topic>Male</topic><topic>MEDICINE</topic><topic>Middle Aged</topic><topic>MOTION</topic><topic>Movement</topic><topic>NEOPLASMS</topic><topic>NMR IMAGING</topic><topic>NUCLEAR MEDICINE</topic><topic>Organ Size</topic><topic>ORGANS</topic><topic>Prospective Studies</topic><topic>RADIOLOGY</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>RADIOTHERAPY</topic><topic>Rectum - anatomy & histology</topic><topic>Reproducibility of Results</topic><topic>THERAPY</topic><topic>Tumor Burden</topic><topic>Urinary Bladder - anatomy & histology</topic><topic>Urinary Bladder Neoplasms - pathology</topic><topic>Urinary Bladder Neoplasms - radiotherapy</topic><topic>URINARY TRACT</topic><topic>Urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>McBain, Catherine A., F.R.C.R</creatorcontrib><creatorcontrib>Khoo, Vincent S., F.R.C.R</creatorcontrib><creatorcontrib>Buckley, David L., Ph.D</creatorcontrib><creatorcontrib>Sykes, Jonathan S., M.Sc</creatorcontrib><creatorcontrib>Green, Melanie M., Ph.D</creatorcontrib><creatorcontrib>Cowan, Richard A., F.R.C.R</creatorcontrib><creatorcontrib>Hutchinson, Charles E., F.R.C.R</creatorcontrib><creatorcontrib>Moore, Christopher J., Ph.D</creatorcontrib><creatorcontrib>Price, Patricia M., F.R.C.R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>International journal of radiation oncology, biology, physics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>McBain, Catherine A., F.R.C.R</au><au>Khoo, Vincent S., F.R.C.R</au><au>Buckley, David L., Ph.D</au><au>Sykes, Jonathan S., M.Sc</au><au>Green, Melanie M., Ph.D</au><au>Cowan, Richard A., F.R.C.R</au><au>Hutchinson, Charles E., F.R.C.R</au><au>Moore, Christopher J., Ph.D</au><au>Price, Patricia M., F.R.C.R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of Bladder Motion for Clinical Radiotherapy Practice Using Cine–Magnetic Resonance Imaging</atitle><jtitle>International journal of radiation oncology, biology, physics</jtitle><addtitle>Int J Radiat Oncol Biol Phys</addtitle><date>2009-11-01</date><risdate>2009</risdate><volume>75</volume><issue>3</issue><spage>664</spage><epage>671</epage><pages>664-671</pages><issn>0360-3016</issn><eissn>1879-355X</eissn><abstract>Purpose Organ motion is recognized as the principal source of inaccuracy in bladder radiotherapy (RT), but there is currently little information on intrafraction bladder motion. Methods and Materials We used cine–magnetic resonance imaging (cine-MRI) to study bladder motion relevant to intrafraction RT delivery. On two occasions, a 28 minute cine-MRI sequence was acquired from 10 bladder cancer patients and 5 control participants immediately after bladder emptying, after abstinence from drinking for the preceding hour. From the resulting cine sequences, bladder motion was subjectively assessed. To quantify bladder motion, the bladder was contoured in imaging volume sets at 0, 14, and 28 min to measure changes to bladder volumes, wall displacements, and center of gravity (COG) over time. Results The dominant source of bladder motion during imaging was bladder filling (up to 101% volume increase); rectal and small bowel movements were transient, with minimal impact. Bladder volume changes were similar for all participants. However for bladder cancer patients, wall displacements were larger (up to 58 mm), less symmetrical, and more variable compared with nondiseased control bladders. Conclusions Significant and individualized intrafraction bladder wall displacements may occur during bladder RT delivery. This important source of inaccuracy should be incorporated into treatment planning and verification.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>19473781</pmid><doi>10.1016/j.ijrobp.2008.11.040</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0360-3016 |
| ispartof | International journal of radiation oncology, biology, physics, 2009-11, Vol.75 (3), p.664-671 |
| issn | 0360-3016 1879-355X |
| language | eng |
| recordid | cdi_osti_scitechconnect_21362198 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Aged BLADDER Bladder cancer BODY Case-Control Studies Cine-MRI DIAGNOSTIC TECHNIQUES DISEASES Dose Fractionation Female Hematology, Oncology and Palliative Medicine Humans Intestine, Small - anatomy & histology Intrafraction motion Magnetic Resonance Imaging, Cine Male MEDICINE Middle Aged MOTION Movement NEOPLASMS NMR IMAGING NUCLEAR MEDICINE Organ Size ORGANS Prospective Studies RADIOLOGY RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Rectum - anatomy & histology Reproducibility of Results THERAPY Tumor Burden Urinary Bladder - anatomy & histology Urinary Bladder Neoplasms - pathology Urinary Bladder Neoplasms - radiotherapy URINARY TRACT Urine |
| title | Assessment of Bladder Motion for Clinical Radiotherapy Practice Using Cine–Magnetic Resonance Imaging |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T10%3A15%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_osti_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Assessment%20of%20Bladder%20Motion%20for%20Clinical%20Radiotherapy%20Practice%20Using%20Cine%E2%80%93Magnetic%20Resonance%20Imaging&rft.jtitle=International%20journal%20of%20radiation%20oncology,%20biology,%20physics&rft.au=McBain,%20Catherine%20A.,%20F.R.C.R&rft.date=2009-11-01&rft.volume=75&rft.issue=3&rft.spage=664&rft.epage=671&rft.pages=664-671&rft.issn=0360-3016&rft.eissn=1879-355X&rft_id=info:doi/10.1016/j.ijrobp.2008.11.040&rft_dat=%3Cproquest_osti_%3E67677754%3C/proquest_osti_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=21178415&rft_id=info:pmid/19473781&rft_els_id=S0360301608038534&rfr_iscdi=true |