Acute Hendra virus infection: Analysis of the pathogenesis and passive antibody protection in the hamster model

Abstract Hendra virus (HeV) and Nipah virus (NiV) are recently-emerged, closely related and highly pathogenic paramyxoviruses. We have analysed here the pathogenesis of the acute HeV infection using the new animal model, golden hamster ( Mesocricetus auratus ), which is highly susceptible to HeV inf...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2009-05, Vol.387 (2), p.459-465
Hauptverfasser:	Guillaume, Vanessa, Wong, K. Thong, Looi, R.Y, Georges-Courbot, Marie-Claude, Barrot, Laura, Buckland, Robin, Wild, T. Fabian, Horvat, Branka
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Animal model ANIMALS ANTIBODIES Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal - immunology Antibodies, Viral - administration & dosage Antibodies, Viral - immunology BLOOD VESSELS BODY BRAIN Brain - blood supply Brain - virology CARDIOVASCULAR SYSTEM CENTRAL NERVOUS SYSTEM Cricetinae Cross Reactions Disease Models, Animal DISEASES Emergent disease Endothelium, Vascular - pathology Endothelium, Vascular - virology HAMSTERS Hendra virus Hendra Virus - immunology Hendra Virus - pathogenicity Henipavirus Infections - immunology Henipavirus Infections - prevention & control Henipavirus Infections - virology Hepatitis E virus Immunization, Passive Immunoprophylaxis Infectious Disease INFECTIOUS DISEASES MAMMALS Mesocricetus Mesocricetus auratus MICROORGANISMS MONOCLONAL ANTIBODIES NERVOUS SYSTEM Neutralization Tests Nipah virus Nipah Virus - immunology Nipah Virus - pathogenicity NUCLEIC ACIDS ORGANIC COMPOUNDS ORGANS PARASITES PATHOGENESIS PROTEINS RNA RODENTS SAFETY VACCINES Vasculitis - pathology Vasculitis - virology VERTEBRATES Viral Fusion Proteins - immunology Virulence VIRUSES Viscera - blood supply Viscera - virology
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