Treatment Planning Study to Determine Potential Benefit of Intensity-Modulated Radiotherapy Versus Conformal Radiotherapy for Unresectable Hepatic Malignancies

Purpose To compare intensity-modulated radiotherapy (IMRT) with conformal RT (CRT) for hypofractionated isotoxicity liver RT and explore dose escalation using IMRT for the same/improved nominal risk of liver toxicity in a treatment planning study. Methods and Materials A total of 26 CRT plans were e...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2008-10, Vol.72 (2), p.582-588
Hauptverfasser:	Eccles, Cynthia L., B.Sc, Bissonnette, Jean-Pierre, Ph.D, Craig, Tim, Ph.D, Taremi, Mojgan, M.D, Wu, Xia, Ph.D, Dawson, Laura A., M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Carcinoma, Hepatocellular - diagnostic imaging Carcinoma, Hepatocellular - radiotherapy CARCINOMAS Conformal radiotherapy Dose Fractionation DOSE LIMITS Female generalized equivalent uniform dose gEUD Hematology, Oncology and Palliative Medicine Humans IMRT Intensity-modulated radiotherapy Intestines - radiation effects IRRADIATION LIVER Liver - radiation effects Liver Neoplasms - diagnostic imaging Liver Neoplasms - radiotherapy Liver radiotherapy Male Maximum Tolerated Dose Middle Aged OPTIMIZATION PLANNING RADIATION DOSES Radiation Tolerance Radiography Radiology RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Radiotherapy Planning, Computer-Assisted - methods Radiotherapy, Conformal - methods Radiotherapy, Intensity-Modulated - methods SPINAL CORD Spinal Cord - radiation effects STOMACH Stomach - radiation effects TOXICITY Tumor Burden
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