Response to Therapy and Outcomes in Oropharyngeal Cancer Are Associated With Biomarkers Including Human Papillomavirus, Epidermal Growth Factor Receptor, Gender, and Smoking

Induction chemotherapy and concurrent chemoradiation for responders or immediate surgery for non-responders is an effective treatment strategy head and neck squamous cell carcinoma (HNSCC) of the larynx and oropharynx. Biomarkers that predict outcome would be valuable in selecting patients for thera...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2007-01, Vol.69 (2), p.S109-S111
Hauptverfasser:	Kumar, Bhavna, M.Sc, Cordell, Kitrina G., D.D.S, Lee, Julia S., M.S, Prince, Mark E., M.D, Tran, Huong H., M.D, Wolf, Gregory T., M.D, Urba, Susan G., M.D, Worden, Francis P., M.D, Chepeha, Douglas B., M.D, Teknos, Theodoros N., M.D, Eisbruch, Avraham, M.D, Tsien, Christina I., M.D, Taylor, Jeremy M.G., Ph.D, D'Silva, Nisha J., B.D.S., M.S.D., Ph.D, Yang, Kun, M.D, Kurnit, David M., M.D., Ph.D, Bradford, Carol R., M.D, Carey, Thomas E., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	BIOLOGICAL MARKERS BIOPSY Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - therapy Carcinoma, Squamous Cell - virology CARCINOMAS Chemoradiation CHEMOTHERAPY CLINICAL TRIALS Epidermal growth factor receptor Female GROWTH FACTORS HEAD HEALTH HAZARDS Hematology, Oncology and Palliative Medicine High risk human papillomavirus Human papillomavirus Human papillomavirus 16 Human papillomavirus 16 - isolation & purification Humans LARYNX LYMPHATIC SYSTEM Male Middle Aged NECK Neoplasm Proteins - metabolism Organ sparing clinical trial Oropharyngeal Neoplasms - metabolism Oropharyngeal Neoplasms - therapy Oropharyngeal Neoplasms - virology PATIENTS PHARYNX Radiology RADIOLOGY AND NUCLEAR MEDICINE Receptor, Epidermal Growth Factor - metabolism RECEPTORS Sex Factors Smoking - adverse effects SURGERY Survival Analysis Tonsil cancer Treatment Outcome VIRUSES
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