Geminin is cleaved by caspase-3 during apoptosis in Xenopus egg extracts

Geminin is an important cell cycle regulator having a dual role in cell proliferation and differentiation. During proliferation, Geminin controls DNA synthesis by interacting with the licensing factor Cdt1 and interferes with the onset of differentiation by inhibiting the activity of transcription f...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 2007-09, Vol.361 (2), p.276-280
Hauptverfasser:	Auziol, Camille, Méchali, Marcel, Maiorano, Domenico
Format:	Artikel
Sprache:	eng
Schlagworte:	6-DMAP 60 APPLIED LIFE SCIENCES Adenine - analogs & derivatives Adenine - pharmacology Animals APOPTOSIS Apoptosis - drug effects BIOSYNTHESIS Caspase 3 - metabolism CELL CYCLE Cell Cycle Proteins - metabolism Cell Extracts CELL PROLIFERATION CHROMATIN CLEAVAGE DNA DNA - biosynthesis DNA REPLICATION DNA Replication - drug effects Geminin Genetics IN VITRO Licensing Life Sciences Mitosis - drug effects Ovum - cytology Ovum - drug effects Ovum - enzymology TRANSCRIPTION FACTORS Xenopus Xenopus - metabolism Xenopus Proteins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!