Involvement of over-expressed BMP4 in pentylenetetrazol kindling-induced cell proliferation in the dentate gyrus of adult rats

The dentate gyrus (DG) of the hippocampus is one of a few regions in the adult mammalian brain characterized by ongoing neurogenesis. Proliferation of neural precursors in the granule cell layer of the DG has been identified in pentylenetetrazol (PTZ) kindling epilepsy model, however, little is know...

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Veröffentlicht in:	Biochemical and biophysical research communications 2007-03, Vol.355 (1), p.54-60
Hauptverfasser:	Yin, Jinbo, Ma, Yuxin, Yin, Qing, Xu, Haiwei, An, Ning, Liu, Shiyong, Fan, Xiaotang, Yang, Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Animals Bone Morphogenetic Protein 4 Bone Morphogenetic Proteins - genetics Bone morphogenetic proteins-4 Bromodeoxyuridine BUDR CELL PROLIFERATION Dentate Gyrus - drug effects Dentate Gyrus - physiology EPILEPSY Gene Expression Regulation - drug effects HIPPOCAMPUS Immunohistochemistry In Situ Hybridization Kindling, Neurologic - drug effects Kindling, Neurologic - physiology LABELLING Male Pentylenetetrazol kindling Pentylenetetrazole Polymerase Chain Reaction PROTEINS Rat RATS Rats, Sprague-Dawley SKELETON
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